Evidence map›Paper›PMID 28685252›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Imaging the event-prone coronary artery plaque.

Andreas A Giannopoulos, Dominik C Benz, Christoph Gräni, Ronny R Buechel

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04185493 (Assessment of Coronary Artery Geometry With Coronary CT Angiography), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04185493 unknown statusnot on this mapstarted 2020, after this paper: background citation

Assessment of Coronary Artery Geometry With Coronary CT Angiography: Evaluation of Atherosclerotic Plaque Burden and Composition

Typeobservational_patient_registrySponsorAristotle University Of ThessalonikiRan2020 to 2021Enrolled100ConditionsCoronary Artery Disease, Atherosclerosis, Atherosclerotic Plaque, Stable AnginaArmsCCTA
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Kounis Syndrome Features in Special Populations.Medical sciences (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Review
  7. Assessment of atherosclerosis in multiple myeloma and smoldering myeloma patients usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Article
  9. Review
  10. Fractional flow reserve as the standard of reference: All that glistens is not gold.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  11. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Positron emission tomography, computed tomography and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Review
  12. Multi-slice CT coronary angiography assessment of remodeling index in patients with low- to intermediate-risk stable angina.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2019
    Article
  13. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreas A GiannopoulosDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Dominik C BenzDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Christoph GräniDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Ronny R BuechelDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland. ronny.buechel@usz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute coronary events, the dreaded manifestation of coronary atherosclerosis, remain one of the main contributors to mortality and disability in the developed world. The majority of those events are associated with atherosclerotic plaques-related thrombus formation following an acute disruption, that being rupture or erosion, of an event-prone lesion. These historically termed vulnerable plaques have been the target of numerous benchtop and clinical research endeavors, yet to date without solid results that would allow for early identification and potential treatment. Technological leaps in cardiovascular imaging have provided novel insights into the formation and role of the event-prone plaques. From intracoronary optical coherence tomography that has enhanced our understanding of the pathophysiological mechanisms of plaque disruption, over coronary computed tomography angiography that enables non-invasive serial plaque imaging, and positron emission tomography poised to be rapidly implemented into clinical practice to the budding field of plaque imaging with cardiac magnetic resonance, we summarize the invasive and non-invasive imaging modalities currently available in our armamentarium. Finally, the current status and potential future imaging directions are critically appraised.

Indexed as

Coronary AngiographyCoronary Artery DiseaseCoronary VesselsFollow-Up StudiesHeartHumansMagnetic Resonance AngiographyPlaque, AtheroscleroticPositron-Emission TomographyTomography, Optical CoherenceUltrasonography, Interventionalacute coronary syndromescomputed tomography (CT)Coronary artery diseasePET/CT imagingvulnerable atherosclerotic plaque

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.