Evidence map›Paper›PMID 28685186›Full record

ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2017

The protein pheromone temptin is an attractant of the gastropod Biomphalaria glabrata.

Emmanuel A Pila, Shauna J Peck, Patrick C Hanington

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Unveiling the hemolymphatic miRNome composition of the schistosomiasis vector snailCurrent research in parasitology & vector-borne diseases · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Genes · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emmanuel A PilaSchool of Public Health, University of Alberta, 357F South Academic Building, Edmonton, AB, T6G2G7, Canada.
Shauna J PeckSchool of Public Health, University of Alberta, 357F South Academic Building, Edmonton, AB, T6G2G7, Canada.
Patrick C HaningtonSchool of Public Health, University of Alberta, 357F South Academic Building, Edmonton, AB, T6G2G7, Canada. pch1@ualberta.ca.
University of Alberta · CA

Funding

Natural Sciences and Engineering Research Council of Canada 418540
6 · The paper itself

Abstract

The freshwater snail Biomphalaria glabrata has drawn much research interest by virtue of it being one of the intermediate hosts of the parasitic flatworm Schistosoma mansoni, a causative agent of human schistosomiasis. Schistosomiasis is a chronic disease that affects over 260 million people globally, particularly in tropical and sub-tropical regions. One strategy that has been proposed as a way to prevent human infection by the parasite, involves the use of pheromone traps to lure the snail host away from areas of human activity. This requires an understanding of chemosensory communication in B. glabrata, especially of the chemoattractive factors. Although evidence indicates that specific chemical communication takes place, little is known about chemoattractants produced by the snail itself. Here, we report on the functional characterization of an endogenously produced temptin-like protein (BgTemptin) from B. glabrata and demonstrate that recombinant BgTemptin is attractive to this snail. Exposure of B. glabrata to BgTemptin results in 81% (lane maze) and 70% (T-maze) time spent near to the BgTemptin source. This effect, which is dependent on the concentration of the protein, provides another tool that can be further developed and used in efforts to control and eliminate schistosomiasis.

Indexed as

AnimalsBehavior, AnimalBiomphalariaDose-Response Relationship, DrugMaze LearningPheromonesPhylogenyPheromonesBiomphalaria glabrataGastropodPheromoneSchistosomiasisTemptin

Identifiers

PMID28685186
OpenAlexW2727293891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.