ArticlePediatric nephrology (Berlin, Germany)2017
Health-related quality of life of children with pre-dialysis chronic kidney disease.
Article in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Effect of muscle stretching and isometric exercises on quality of life in children undergoing regular hemodialysis.Pediatric nephrology (Berlin, Germany) · 2024Trial
- Cross-Population Validation of the Pediatric CKD Risk-Prediction Tool.Kidney international reports · 2026Article
- A cost-effective innovation in anaemia management for paediatric patients with haemodialysis-dependent chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Quality of life in children at different stages of chronic kidney disease in a developing country.Pediatric nephrology (Berlin, Germany) · 2025Article
- Common mental health conditions and considerations in pediatric chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2024Review
- The Effect of Sleep Habits on Quality of Life in Pediatric Patients With Chronic Kidney Disease.Cureus · 2024Article
- Longitudinal changes of health-related quality of life in childhood chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- The Use of Patient-Reported Outcome Measures in Daily Clinical Practice of a Pediatric Nephrology Department.International journal of environmental research and public health · 2022Article
- Article
- Study of the association between generic and disease-specific quality of life and behavior problems in pediatric patients with chronic kidney disease stage 3 or higher and the quality of life and mental health of their primary caregivers.Pediatric nephrology (Berlin, Germany) · 2021Article
- Incidence of and risk factors for short stature in children with chronic kidney disease: results from the KNOW-Ped CKD.Pediatric nephrology (Berlin, Germany) · 2021Article
- Intellectual Functioning of Pediatric Patients with Chronic Kidney Disease: Results from the KNOW-Ped CKD.Journal of Korean medical science · 2021Article
- A longitudinal analysis of the effect of anemia on health-related quality of life in children with mild-to-moderate chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2020Article
- Targeted Exome Sequencing Provided Comprehensive Genetic Diagnosis of Congenital Anomalies of the Kidney and Urinary Tract.Journal of clinical medicine · 2020Article
- Anemia and Iron Deficiency in Children with Chronic Kidney Disease (CKD): Data from the Know-Ped CKD Study.Journal of clinical medicine · 2019Article
- Quality of life, depression and anxiety in children and adolescents with CKD and their primary caregivers.Jornal brasileiro de nefrologiaObservational
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Authors and funding
14 authors.
Funding
Abstract
backgroundThe goal of this study was to evaluate the quality of life (QOL) of Asian children with pre-dialysis chronic kidney disease (CKD) and to reveal the factors influencing the QOL of children with CKD.
methodsWe performed a cross-sectional study of the PedsQL 4.0 Generic Core Scale Module in the KNOW-PedCKD (KoreaN cohort study for Outcome in patients with Pediatric Chronic Kidney Disease) cohort, and compared the child self-reported and parent proxy-reported QOL of the pediatric cohort. From 2011 through 2016, a total of 376 children with CKD were enrolled after informed consent was obtained from parents or caregivers in seven pediatric nephrology centers.
resultsIn parent proxy-reports, male patients had a better QOL than female patients in the Physical Functioning category. In child self-reports, male patients had better QOL than female patients in the Physical, Emotional, and School Functioning categories. According to CKD stage, there were significant differences in the QOL score in all categories of parent proxy-reports, and patients with higher CKD stage (lower glomerular filtration rate) had a worse QOL. Growth parameters showed a significantly positive correlation with the QOL score in all categories.
conclusionsThe QOL of children with predialysis CKD is affected by various factors, including sex, glomerular filtration rate (GFR), socio-economic status, existence of co-morbidities, anemia, growth retardation, and behavioral disorders. To improve their QOL, it is important to objectively understand the respective effects of these factors and attempt early intervention.
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