Evidence map›Paper›PMID 28684913›Full record

ArticleInternational journal of nanomedicine2017

Preparation and antioxidant properties of selenium nanoparticles-loaded chitosan microspheres.

Kaikai Bai, Bihong Hong, Jianlin He, Zhuan Hong, Ran Tan

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 192 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Review
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  8. Article
  9. Article
  10. Recent Progress in Selenium Nanomedicines for Ocular Diseases.International journal of nanomedicine · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
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  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution.

Kaikai BaiThird Institute of Oceanography.
Bihong HongThird Institute of Oceanography.
Jianlin HeThird Institute of Oceanography.
Zhuan HongThird Institute of Oceanography.
Ran TanThird Institute of Oceanography.
Institute of Oceanography

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium nanoparticles (SeNPs), as a special form of selenium (Se) supplement, have attracted worldwide attention due to their favorable properties and unique bioactivities. Herein, an eco-friendly and economic way to prepare stable SeNPs is introduced. SeNPs were synthesized in aqueous chitosan (CTS) and then embedded into CTS microspheres by spray-drying, forming selenium nanoparticles-loaded chitosan microspheres (SeNPs-M). The physicochemical properties including morphology, elemental state, size distribution and surface potential were investigated. Institute of Cancer Research mice were used as model animal to evaluate the bioactivities of SeNPs-M. Trigonal-phase SeNPs of ~35 nm were synthesized, and SeNPs-M physically embedding those SeNPs were successfully prepared. Amazingly, acute toxicity test indicated that SeNPs-M were much safer than selenite in terms of Se dose, with a LD

Indexed as

AnimalsAntioxidantsChitosanGlutathione PeroxidaseMiceMice, Inbred ICRMicrospheresNanoparticlesOxidation-ReductionSeleniumToxicity Tests, AcuteAntioxidantsChitosanGlutathione PeroxidaseSeleniumantioxidantchitosanmicrospherenanoselenium

Identifiers

PMID28684913
PMCPMC5485894
OpenAlexW2694562274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.