Evidence map›Paper›PMID 28684906›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2017

Hospital admissions and mortality in patients with COPD exacerbations and vertebral body compression fractures.

Sergi Pascual-Guardia, Diana Badenes-Bonet, Clara Martin-Ontiyuelo, Flavio Zuccarino, Judith Marín-Corral, Alejandro Rodríguez, Esther Barreiro, Joaquim Gea

Open access · goldAbstract readValidation Study
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. COPD and Osteoporosis: Associated Factors in Patients Treated with Inhaled Corticosteroids.International journal of chronic obstructive pulmonary disease · 2020
    Article
  9. Management of the COPD Patient with Comorbidities: An Experts Recommendation Document.International journal of chronic obstructive pulmonary disease · 2020
    Article
  10. Article
  11. Increased rate of osteoporosis, low lean mass, and fragility fractures in COPD patients: association with disease severity.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
  12. Treatable Traits in COPD - A Proposed Approach.International journal of chronic obstructive pulmonary disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sergi Pascual-GuardiaDepartment of Respiratory Medicine, Hospital del Mar-IMIM, Barcelona, Spain.
Diana Badenes-BonetDepartment of Respiratory Medicine, Hospital del Mar-IMIM, Barcelona, Spain.
Clara Martin-OntiyueloDepartment of Respiratory Medicine, Hospital del Mar-IMIM, Barcelona, Spain.
Flavio ZuccarinoDepartment of Imaging, Hospital del Mar, Barcelona, Spain.
Judith Marín-CorralIntensive Care Unit, Hospital del Mar, Research Group in Critical Disorders (GREPAC), IMIM, Barcelona, Spain.
Alejandro RodríguezCIBERES, ISCiii. Madrid, Spain.
Esther BarreiroDepartment of Respiratory Medicine, Hospital del Mar-IMIM, Barcelona, Spain.
Joaquim GeaDepartment of Respiratory Medicine, Hospital del Mar-IMIM, Barcelona, Spain.
Hospital Del Mar · ESUnidades Centrales Científico-Técnicas · ESPompeu Fabra University · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVertebral compression fractures (VCF) are common in COPD patients, with osteoporosis being the main cause. The clinical impact of VCF derives mostly from both pain and chest deformity, which may lead to ventilatory and physical activity limitations. Surprisingly, the consequences of VCF on the quality outcomes of hospital care are poorly known.

objectiveTo assess these indicators in patients hospitalized due to a COPD exacerbation (ECOPD) who also have VCF.

methodsClinical characteristics and quality care indicators were assessed in two one-year periods, one retrospective (exploratory) and one prospective (validation), in all consecutive patients hospitalized for ECOPD. Diagnosis of VCF was based on the reduction of >20% height of the vertebral body evaluated in standard lateral chest X-ray (three independent observers).

resultsFrom the 248 patients admitted during the exploratory phase, a third had at least one VCF. Underdiagnosis rate was 97.6%, and patients with VCF had more admissions (normalized for survival), longer hospital stays, and higher mortality than patients without (4 [25th-75th percentiles, 2-8] vs 3 [1-6] admissions,

conclusionAlthough VCF is frequently underdiagnosed in patients hospitalized for ECOPD, it is strongly associated with a worse prognosis and quality care outcomes.

Indexed as

Patient AdmissionAgedAged, 80 and overFemaleFractures, CompressionHumansKaplan-Meier EstimateLength of StayLogistic ModelsMaleMiddle AgedOdds RatioPrognosisProspective StudiesPulmonary Disease, Chronic ObstructiveQuality Indicators, Health CareCOPDhospitalizationsprognosisvertebral fracture

Identifiers

PMID28684906
PMCPMC5485891
OpenAlexW2645040378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.