ArticleScientific reports2017
The normal environment delays the development of multisensory integration.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- The brain can develop conflicting multisensory principles to guide behavior.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Multisensory training improves the development of spatial cognition after sight restoration from congenital cataracts.iScience · 2024Article
- The Development of Multisensory Integration at the Neuronal Level.Advances in experimental medicine and biology · 2024Article
- Noise-rearing precludes the behavioral benefits of multisensory integration.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Atypical development of causal inference in autism inferred through a neurocomputational model.Frontiers in computational neuroscience · 2023Article
- Association Cortex Is Essential to Reverse Hemianopia by Multisensory Training.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Multisensory enhancement of overt behavior requires multisensory experience.The European journal of neuroscience · 2021Article
- Using superior colliculus principles of multisensory integration to reverse hemianopia.Neuropsychologia · 2020Article
- Reversing Hemianopia by Multisensory Training Under Anesthesia.Frontiers in systems neuroscience · 2020Article
- Experience Creates the Multisensory Transform in the Superior Colliculus.Frontiers in integrative neuroscience · 2020Article
- Cross-Modal Competition: The Default Computation for Multisensory Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Integration of visual and whisker signals in rat superior colliculus.Scientific reports · 2018Article
- Development of the Mechanisms Governing Midbrain Multisensory Integration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Evidence for Brainstem Contributions to Autism Spectrum Disorders.Frontiers in integrative neuroscience · 2018Review
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Authors and funding
4 authors.
Funding
Abstract
Multisensory neurons in animals whose cross-modal experiences are compromised during early life fail to develop the ability to integrate information across those senses. Consequently, they lack the ability to increase the physiological salience of the events that provide the convergent cross-modal inputs. The present study demonstrates that superior colliculus (SC) neurons in animals whose visual-auditory experience is compromised early in life by noise-rearing can develop visual-auditory multisensory integration capabilities rapidly when periodically exposed to a single set of visual-auditory stimuli in a controlled laboratory paradigm. However, they remain compromised if their experiences are limited to a normal housing environment. These observations seem counterintuitive given that multisensory integrative capabilities ordinarily develop during early life in normal environments, in which a wide variety of sensory stimuli facilitate the functional organization of complex neural circuits at multiple levels of the neuraxis. However, the very richness and inherent variability of sensory stimuli in normal environments will lead to a less regular coupling of any given set of cross-modal cues than does the otherwise "impoverished" laboratory exposure paradigm. That this poses no significant problem for the neonate, but does for the adult, indicates a maturational shift in the requirements for the development of multisensory integration capabilities.
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Registered trials
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