ArticleScientific reports2017
Inner ear ossification and mineralization kinetics in human embryonic development - microtomographic and histomorphological study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Isotopic Values of Prenatal Development: δAmerican journal of biological anthropology · 2026Article
- Critical Review of Hearing Rehabilitation in Pediatric Oncology: Specific Considerations and Barriers.Current oncology (Toronto, Ont.) · 2025Review
- Upregulated Expression and Shifted Distribution of Melatonin and Its Synthesizing Enzymes From Postnatal to Young Adult Rat Cochleae.Developmental neurobiology · 2025Article
- Morphological, Histological and Morphometrical Aspects of Auditory Ossicles in Pig Fetuses (Animals : an open access journal from MDPI · 2025Article
- Where Typhoeus lived:iScience · 2025Article
- Expression of Neurotrophins and Its Receptors During Fetal Development in the Human Cochlea.International journal of molecular sciences · 2024Article
- Timing and Graded BMP Signalling Determines Fate of Neural Crest and Ectodermal Placode Derivatives from Pluripotent Stem Cells.Biomedicines · 2024Review
- Convergent evolution in Afrotheria and non-afrotherians demonstrates high evolvability of the mammalian inner ear.Nature communications · 2024Article
- First evidence of the link between internal and external structure of the human inner ear otolith system using 3D morphometric modeling.Scientific reports · 2023Article
- Current Advances in Adeno-Associated Virus-Mediated Gene Therapy to Prevent Acquired Hearing Loss.Journal of the Association for Research in Otolaryngology : JARO · 2022Review
- The Relationship Between the Third Window Abnormalities and Inner Ear Malformations in Children with Hearing Loss.The journal of international advanced otology · 2021Article
- Fetal development of the carotid canal with special reference to a contribution of the sphenoid bone and pharyngotympanic tube.Anatomy & cell biology · 2021Article
- Influence of physical activity before and during pregnancy on infant's sleep and neurodevelopment at 1-year-old.Scientific reports · 2021Article
- Assessment of the Membranous Labyrinth in Infants Using a Heavily T2-weighted 3D FLAIR Sequence without Contrast Agent Administration.AJNR. American journal of neuroradiology · 2021Observational
- Human auditory ossicles as an alternative optimal source of ancient DNA.Genome research · 2020Article
- Growth and cellular patterning during fetal human inner ear development studied by a correlative imaging approach.BMC developmental biology · 2019Article
- Neural crest contributions to the ear: Implications for congenital hearing disorders.Hearing research · 2019Review
- Does 3-T fetal MRI induce adverse acoustic effects in the neonate? A preliminary study comparing postnatal auditory test performance of fetuses scanned at 1.5 and 3 T.Pediatric radiology · 2019Article
- Development of ossification in the vertical semicircular canals: tomographic study.Surgical and radiologic anatomy : SRA · 2018Article
- Characteristics of the Facial Canal-Lateral Canal Dehiscence: The Under-recognized Third Window.OTO openArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little is known about middle and inner ear development during the second and third parts of human fetal life. Using ultra-high resolution Microcomputed Tomography coupled with bone histology, we performed the first quantitative middle and inner ear ossification/mineralization evaluation of fetuses between 17 and 39 weeks of gestational age. We show distinct ossification paces between ossicles, with a belated development of the stapes. A complete cochlear bony covering is observed within the time-frame of the onset of hearing, whereas distinct time courses of ossification for semicircular canal envelopes are observed in relation to the start of vestibular functions. The study evidences a spatio-temporal relationship between middle and inner ear structure development and the onset of hearing and balance, critical senses for the fetal adaptation to birth.
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