Evidence map›Paper›PMID 28684715›Full record

ArticleMolecules (Basel, Switzerland)2017

Design, Synthesis and Bioactivities of Novel 1,4-Pentadien-3-one Derivatives Containing a Substituted Pyrazolyl Moiety.

Cuili Chen, Jia Chen, Haiying Gu, Ning Bao, Hong Dai

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cuili ChenCollege of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China. cleancucumber@163.com.
Jia ChenCollege of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, China. 15642891665@163.com.
Haiying GuCollege of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China. guhy99@21cn.com.
Ning BaoSchool of Public Health, Nantong University, Nantong 226019, China. ningb2000@yahoo.com.
Hong DaiCollege of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, China. daihong_2015@aliyun.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, in order to find novel biologically active penta-1,4-dien-3-one derivatives, a series of penta-1,4-dien-3-one compounds containing a substituted pyrazole subunit were designed and synthesized. Their structures were characterized by ¹H-NMR,

Indexed as

AlkadienesCell Line, TumorCell ProliferationCurcuminDrug DesignHumansNitrilesPyrazolesPyrimidinesAlkadienesAZD 1480CurcuminNitrilespyrazolePyrazolesPyrimidinesruxolitinibbiological activitypenta-1,4-dien-3-onepyrazolesynthesis

Identifiers

PMID28684715
PMCPMC6152210

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.