Evidence map›Paper›PMID 28684617›Full record

ArticleCirculation research2017

EZ Switch From EZH2 to EZH1: Histone Methylation Opens a Window of Cardiac Regeneration.

Hyun Kook, Sang-Beom Seo, Rajan Jain

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Circulation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Epigenetics in diabetic cardiomyopathy.Clinical epigenetics · 2024
    Review
  7. Article
  8. AmedRxiv : the preprint server for health sciences · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hyun KookFrom the Department of Pharmacology, Chonnam National University Medical School, Gwangju, South Korea (H.K.); Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, South Korea (S.-B.S.); and Departments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Institute of Regenerative Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (R.J.). kookhyun@chonnam.ac.kr.
Sang-Beom SeoFrom the Department of Pharmacology, Chonnam National University Medical School, Gwangju, South Korea (H.K.); Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, South Korea (S.-B.S.); and Departments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Institute of Regenerative Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (R.J.).
Rajan JainFrom the Department of Pharmacology, Chonnam National University Medical School, Gwangju, South Korea (H.K.); Department of Life Science, College of Natural Sciences, Chung-Ang University, Seoul, South Korea (S.-B.S.); and Departments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Institute of Regenerative Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (R.J.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HistonesPolycomb Repressive Complex 2Enhancer of Zeste Homolog 2 ProteinMethylationRegenerationEnhancer of Zeste Homolog 2 ProteinHistonesPolycomb Repressive Complex 2cardiac regenerationEditorialsembryonic stem cellEZH1/2H3K27me3heart development

Identifiers

PMID28684617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.