ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017
Potential involvement of lactate and interleukin-6 in the appetite-regulatory hormonal response to an acute exercise bout.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Circulating Myokine Responses to Acute Endurance Exercise and Their Role in Immunoregulation: A Systematic Review and Meta-Analysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Pooled it
- Fasting appetite-related gut hormone responses after weight loss induced by calorie restriction, exercise, or both in people with overweight or obesity: a meta-analysis.International journal of obesity (2005) · 2025Pooled it
- Post-exercise energy intake: do the intensity and mode of exercise matter? A systematic review and meta-analysis comparing high-intensity interval with moderate-intensity continuous protocols.European journal of clinical nutrition · 2022Pooled it
- Trial
- Plasma LEAP-2 Following a Low-Calorie Diet with or without Interval Exercise in Women with Obesity.Nutrients · 2023Trial
- The effect of blood flow restriction exercise on N-lactoylphenylalanine and appetite regulation in obese adults: a cross-design study.Frontiers in endocrinology · 2023Trial
- Greater lactate accumulation following an acute bout of high-intensity exercise in males suppresses acylated ghrelin and appetite postexercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Trial
- Molecular vehicles for therapeutic delivery of lactate in exercise and medicine.Sports medicine and health science · 2026Review
- Exercise Timing and its Effects on Eating Behavior, Weight, and Body Composition: A Systematic Scoping Review to Identify Gaps and Inform Future Research.Current nutrition reports · 2026Article
- Moderate to Vigorous Physical Activity as a Cause of Dietary Restriction in Eating Disorders.The International journal of eating disorders · 2025Review
- Article
- The value of blood lactate and lactate clearance rate in evaluating the prognosis of athletes with heat illness of varying degrees after high-intensity exercise.BMC sports science, medicine & rehabilitation · 2025Article
- The Art and Science of Antidiabetic Medications and Obesity Management.Mini reviews in medicinal chemistry · 2025Review
- Proof-of-concept of a prior validated LC-MS/MS method for detection ofFrontiers in sports and active living · 2025Article
- Acute effect of exercise on appetite-related factors in males with obesity: A pilot study.Physiological reports · 2024Article
- Exercise as a Therapeutic Strategy for Obesity: Central and Peripheral Mechanisms.Metabolites · 2024Review
- Decreased mitochondrial-related gene expression in adipose tissue after acute sprint exercise in humans: A pilot study.Physiological reports · 2024Article
- The effects of acute aerobic exercise on appetite-regulating parameters and energy intake in males with obesity.Health science reports · 2024Article
- Effects of wearing a KF94 face mask on performance, perceptual parameters, and physiological responses during resistance exercise.Physical activity and nutrition · 2024Article
- Exercise-induced appetite suppression: An update on potential mechanisms.Physiological reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-intensity exercise suppresses appetite partly through changes in peripheral appetite-regulating hormones. Lactate and IL-6 mediate the release of these hormones in animal/cell models and may provide a mechanistic link between exercise intensity and appetite regulation. The current study examined changes in appetite-regulating hormones, lactate, and IL-6 after different intensities of running. Eight males completed four experimental sessions:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.