ArticleAJNR. American journal of neuroradiology2017
Identification and Quantitative Assessment of Different Components of Intracranial Atherosclerotic Plaque by Ex Vivo 3T High-Resolution Multicontrast MRI.
Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- Predictive Value of Baseline High-Resolution MRI Features for In-Stent Restenosis in Symptomatic Nonacute Intracranial Atherosclerotic Occlusion.Cardiovascular and interventional radiology · 2026Article
- Atherosclerotic Plaque Characterization Magnetic Resonance Imaging In Vitro at 1.5 Tesla for the Assessment of Coronary Artery Disease.Journal of clinical medicine · 2026Article
- Atherosclerotic plaque distribution and characteristics in young patients with stroke/transient ischemic attack: insights from MR vessel wall imaging and comparison with older counterparts.Quantitative imaging in medicine and surgery · 2026Article
- A hybrid model based on vessel wall magnetic resonance imaging predicts recurrence in posterior circulation ischemic stroke: a multi-institutional study.Journal of neurointerventional surgery · 2026Article
- Prediction of Occlusion Duration in Nonacute Intracranial Large Artery Through High-Resolution Vessel Wall Imaging.Journal of the American Heart Association · 2025Article
- Comparison of computer-aided quantitative measurement and physician visual assessment in the evaluation of intracranial atherosclerotic stenosis: a vessel wall magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2024Article
- Wall characteristics of atherosclerotic middle cerebral arteries in patients with single or multiple infarcts: A high-resolution MRI Study.Frontiers in neurology · 2022Article
- Histology-Verified Intracranial Artery Calcification and Its Clinical Relevance With Cerebrovascular Disease.Frontiers in neurology · 2021Review
- Why is middle cerebral artery plaque augmented by contrast media? A phantom study using middle cerebral artery stenotic silicon model.Neuroradiology · 2019Article
- Inter-rater and scan-rescan reproducibility of the detection of intracranial atherosclerosis on contrast-enhanced 3D vessel wall MRI.The British journal of radiology · 2019Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 5 countries.
Funding
Abstract
background and purposeHigh-resolution 3T MR imaging can visualize intracranial atherosclerotic plaque. However, histologic validation is still lacking. This study aimed to evaluate the ability of 3T MR imaging to identify and quantitatively assess intracranial atherosclerotic plaque components ex vivo with histologic validation. MATERIALS AND
methodsFifty-three intracranial arterial specimens with atherosclerotic plaques from 20 cadavers were imaged by 3T MR imaging with T1, T2, and proton-density-weighted FSE and STIR sequences. The signal characteristics and areas of fibrous cap, lipid core, calcification, fibrous tissue, and healthy vessel wall were recorded on MR images and compared with histology. Fibrous cap thickness and maximum wall thickness were also quantified. The percentage of areas of the main plaque components, the ratio of fibrous cap thickness to maximum wall thickness, and plaque burden were calculated and compared.
resultsThe signal intensity of the lipid core was significantly lower than that of the fibrous cap on T2-weighted, proton-density, and STIR sequences (
conclusionsEx vivo 3T MR imaging can accurately identify and quantitatively assess intracranial atherosclerotic plaque components, providing a direct reference for in vivo intracranial plaque imaging.
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