ArticleCardiovascular diabetology2017
Westernization of lifestyle affects quantitative and qualitative changes in adiponectin.
Article in Cardiovascular diabetology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Exploring the Prevalence and Components of Metabolic Syndrome in Sub-Saharan African Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis.Journal of obesity · 2024Pooled it
- The Prevalence of Metabolic Syndrome in Ethiopian Population: A Systematic Review and Meta-analysis.Journal of obesity · 2020Pooled it
- Prevalence and determinants of metabolic syndrome among patients with type 2 diabetes mellitus in the Buea Health District, South West Region, Cameroon.The Pan African medical journal · 2026Article
- The Role of Adiponectin andGenes · 2025Review
- The impact of overseas assignments on metabolic factors: Panasonic cohort study 23.Journal of occupational health · 2024Article
- Metabolic syndrome and associated factors amongFrontiers in endocrinology · 2024Article
- Dietary Vitamins A, C, and Potassium Intake Is Associated With Narrower Retinal Venular Caliber.Frontiers in medicine · 2022Article
- A 50-year history of the health impacts of Westernization on the lifestyle of Japanese Americans: A focus on the Hawaii-Los Angeles-Hiroshima Study.Journal of diabetes investigation · 2020Review
- Plasma omentin levels are inversely associated with atherosclerosis in type 2 diabetes patients with increased plasma adiponectin levels: a cross-sectional study.Cardiovascular diabetology · 2019Article
- Article
- Alteration of gut microbiota by a Westernized lifestyle and its correlation with insulin resistance in non-diabetic Japanese men.Journal of diabetes investigation · 2019Article
- The association between serum adiponectin and 3-month outcome after ischemic stroke.Cardiovascular diabetology · 2019Observational
- Mechanism and Potential of Egg Consumption and Egg Bioactive Components on Type-2 Diabetes.Nutrients · 2019Review
- Metabolomic profiling implicates adiponectin as mediator of a favorable lipoprotein profile associated with NT-proBNP.Cardiovascular diabetology · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough Japanese-Americans and native Japanese share the same genetic predispositions, they live different lifestyles, resulting in insulin resistance in Japanese-Americans. We investigated whether the quantitative and qualitative changes in adiponectin (APN) due to differences in lifestyle contribute to the development of insulin resistance.
methodsWe evaluated 325 native Japanese in Hiroshima, Japan and 304 Japanese-Americans in Los Angeles, the United States, who were aged between 30 and 70 years and underwent medical examinations between 2009 and 2010. All participants underwent a 75-g oral glucose tolerance test (OGTT) to assess their glucose tolerance. The insulin response to oral glucose load, the Matsuda index, total APN levels, and C1q-APN/total-APN ratios were compared between native Japanese and Japanese-Americans.
resultsCompared with the native Japanese, the Japanese-Americans had significantly lower Matsuda index and higher area under the curve values for serum insulin concentration during OGTT in the normal glucose tolerance (NGT) and impaired glucose tolerance (IGT) groups, but not in the diabetes mellitus (DM) group. Furthermore, the Japanese-Americans had significantly lower total APN levels and higher C1q-APN/total-APN ratios than the native Japanese in the NGT and IGT groups, but not in the DM group.
conclusionsThis study suggested that, in Japanese people, the westernization of their lifestyle might affect quantitative and qualitative changes in APN and induce insulin resistance.
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