Evidence map›Paper›PMID 28683745›Full record

ArticleJournal of neuroengineering and rehabilitation2017

Topographical measures of functional connectivity as biomarkers for post-stroke motor recovery.

Gavin R Philips, Janis J Daly, José C Príncipe

Abstract read
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  6. Human-AI Cooperation in Healthcare and Rehabilitation.Delaware journal of public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gavin R PhilipsComputational NeuroEngineering Laboratory, Department of Electrical and Computer Engineering, University of Florida, Gainesville, Florida, USA. philips.gavin@gmail.com.ORCID 0000-0002-8035-0152
Janis J DalyDepartment of Neurology, University of Florida, Gainesville, Florida, USA.
José C PríncipeComputational NeuroEngineering Laboratory, Department of Electrical and Computer Engineering, University of Florida, Gainesville, Florida, USA.

Funding

Non-Invasive Brain-Signal Training To Induce Motor Control Recovery after StrokeR01NS063275 · NINDS · UNIVERSITY OF FLORIDA · PI DALY, JANIS J. · 2008 to 2011
$1.1M
NINDS NIH HHS R01 NS063275
6 · The paper itself

Abstract

backgroundBiomarkers derived from neural activity of the brain present a vital tool for the prediction and evaluation of post-stroke motor recovery, as well as for real-time biofeedback opportunities.

methodsIn order to encapsulate recovery-related reorganization of brain networks into such biomarkers, we have utilized the generalized measure of association (GMA) and graph analyses, which include global and local efficiency, as well as hemispheric interdensity and intradensity. These methods were applied to electroencephalogram (EEG) data recorded during a study of 30 stroke survivors (21 male, mean age 57.9 years, mean stroke duration 22.4 months) undergoing 12 weeks of intensive therapeutic intervention.

resultsWe observed that decreases of the intradensity of the unaffected hemisphere are correlated (r

conclusionsThese topological measures show promise for prognosis and evaluation of therapeutic outcomes, as well as potential application to BCI-enabled biofeedback.

Indexed as

Stroke RehabilitationAdultAgedAlgorithmsBiofeedback, PsychologyBiomarkersBiomechanical PhenomenaCerebral CortexElectroencephalographyFemaleFunctional LateralityHumansMaleMiddle AgedNerve NetPredictive Value of TestsBiomarkersElectroencephalography (EEG)Functional connectivityGeneralized measure of association (GMA)Graph theoryPlasticityRehabilitationStroke

Identifiers

PMID28683745
PMCPMC5501348

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.