ArticleBMC neurology2017
Post-operative re-bleeding in patients with hypertensive ICH is closely associated with the CT blend sign.
Article in BMC neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- Associations between Hematoma Density, Hematoma Evacuation Efficacy, and In-Hospital Mortality in Patients Undergoing Minimally Invasive Surgery after Intracerebral Hemorrhage.Neurocritical care · 2026Article
- Establishment and verification of a clinical prediction model for hematoma expansion in the acute phase of hypertensive intracerebral hemorrhage.Neurosurgical review · 2026Article
- Quantification of hounsfield unit difference in heterogeneous hematoma predicts poor functional outcomes in acute intracerebral hemorrhage.Scientific reports · 2025Observational
- Heterogeneous hematoma density predicts poor outcome in patients with supratentorial intracerebral hemorrhage after craniotomy.BMC neurology · 2025Article
- Quantitative Shape Irregularity and Density Heterogeneity of Preoperative Hematoma Can Predict Rebleeding following Minimally Invasive Catheter Evacuation for Intracerebral Hemorrhage.AJNR. American journal of neuroradiology · 2025Article
- Risk of postoperative major adverse cerebrovascular events in patients with spontaneous intracranial hematoma stratified by type 2 diabetes mellitus.Frontiers in human neuroscience · 2025Article
- The predictive value of stereotactic surgery guided by CTA angiographic point sign for secondary hematoma expansion following surgery in patients with moderate-volume basal ganglia hematoma.Frontiers in neurology · 2025Article
- Value of the spot sign combined with the blend sign for predicting the outcome of patients with intracerebral hemorrhage who have undergone stereotactic minimally invasive surgery.Frontiers in neurology · 2025Article
- Predicting postoperative rehemorrhage in hypertensive intracerebral hemorrhage using noncontrast CT radiomics and clinical data with an interpretable machine learning approach.Scientific reports · 2024Article
- The predictive role of the nomogram based on clinical characteristics and thromboelastography markers for rebleeding after hypertensive intracerebral hemorrhage.Biochemistry and biophysics reports · 2024Article
- Blend Sign and Haemorrhage Location and Volume Predict Late Recurrence and Mortality in Intracerebral Haemorrhage Patients.Journal of clinical medicine · 2023Article
- Research advances in imaging markers for predicting hematoma expansion in intracerebral hemorrhage: a narrative review.Frontiers in neurology · 2023Review
- Computed tomography in acute intracerebral hemorrhage: neuroimaging predictors of hematoma expansion and outcome.Insights into imaging · 2022Review
- A nomogram to predict the risk of postoperative intracranial rebleeding in patients with spontaneous intracranial hematoma.Neurosurgical review · 2022Article
- Irregular-Shaped Hematoma Predicts Postoperative Rehemorrhage After Stereotactic Minimally Invasive Surgery for Intracerebral Hemorrhage.Frontiers in neurology · 2022Article
- Is the CT Blend Sign Composed of Two Parts of Blood with Different Age?Neurocritical care · 2021Article
- Association of Satellite Sign with Postoperative Rebleeding in Patients Undergoing Stereotactic Minimally Invasive Surgery for Hypertensive Intracerebral Haemorrhage.Current medical science · 2021Article
- The initial CT blend sign is not associated with poor patient outcomes after stereotactic minimally invasive surgery.BMC neurology · 2021Article
- Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu.JCI insight · 2021Article
- Computed Tomography Imaging Predictors of Intracerebral Hemorrhage Expansion.Current neurology and neuroscience reports · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundsIntracranial post-operative re-haemorrhage is an important complication in patients with hypertensive intracerebral haemorrhage (ICH). The purpose of the present study was to determine the value of the computed tomography (CT) blend sign in predicting post-operative re-haemorrhage in patients with ICH.
methodsA total of 126 patients with ICH were included in the present study. All the patients underwent standard stereotactic minimally invasive surgery(MIS) to remove the ICH within 24 h following admission. There were 41 patients with a blend sign on initial CT and 85 patients without a blend sign on the initial CT. Multivariable logistic regression analyses were performed to assess the relationship between the presence of the blend sign on the non-enhanced admission CT scan and post-operative re-haemorrhage.
resultsPost-operative re-haemorrhage occurred in 24 of the 41 patients with the blend sign, and in 9 of the 85 patients without the blend sign. The incidence of re-haemorrhage was significantly different between the groups. The multivariate logistic regression analysis demonstrated that the initial Glasgow coma scale score (p = 0.002) and blend sign (P < 0.00) on the initial CT scan are independent predictors of post-operative re-haemorrhage. The sensitivity, specificity, and positive and negative predictive values of the blend sign for predicting post-operative re-haemorrhage were 72.7, 81.7, 58.5 and 89.4%, respectively.
conclusionsThe presence of the blend sign on the initial CT scan is closely associated with post-operative re-haemorrhage in patients with ICH who undergo stereotactic MIS.
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