ArticleBiointerphases2017
Water contact angle is not a good predictor of biological responses to materials.
Article in Biointerphases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Improved Surface Properties and Enhanced Cell Adhesion on Poly-ε-Caprolactone for Heart Valve Tissue Engineering Applications via HInternational journal of molecular sciences · 2026Article
- Catheter mechanoprophylaxis againstMicrobiology (Reading, England) · 2026Article
- High-Throughput Analysis of Protein Adsorption to a Large Library of Polymers Using Liquid Extraction Surface Analysis-Tandem Mass Spectrometry (LESA-MS/MS).Analytical chemistry · 2025Article
- Carbon Source and Substrate Surface Affect Biofilm Formation by the Plant-Associated BacteriumInternational journal of molecular sciences · 2024Article
- A facile one step route that introduces functionality to polymer powders for laser sintering.Nature communications · 2024Article
- A potential alternative to fungicides using actives-free (meth)acrylate polymers for protection of wheat crops from fungal attachment and infection.Green chemistry : an international journal and green chemistry resource : GC · 2023Article
- Fabrication of Solvent-Free PCL/β-TCP Composite Fiber for 3D Printing: Physiochemical and Biological Investigation.Polymers · 2023Article
- Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation.Science advances · 2023Article
- Surface Free Energy Dominates the Biological Interactions of Postprocessed Additively Manufactured Ti-6Al-4V.ACS biomaterials science & engineering · 2022Article
- Tuning Contact Angles of Aqueous Droplets on Hydrophilic and Hydrophobic Surfaces by Surfactants.The journal of physical chemistry. B · 2022Article
- Cyto- and bio-compatibility assessment of plasma-treated polyvinylidene fluoride scaffolds for cardiac tissue engineering.Frontiers in bioengineering and biotechnology · 2022Article
- Impact of surface topography on the bacterial attachment to micro- and nano-patterned polymer films.Surfaces and interfaces · 2021Article
- Predicting the In Vivo Performance of Cardiovascular Biomaterials: Current Approaches In Vitro Evaluation of Blood-Biomaterial Interactions.International journal of molecular sciences · 2021Review
- Multifunctional Scaffolds and Synergistic Strategies in Tissue Engineering and Regenerative Medicine.Pharmaceutics · 2021Review
- High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology.Chemical reviews · 2021Review
- Protein- and Cell-Resistance of Zwitterionic Peptide-Based Self-Assembled Monolayers: Anti-Biofouling Tests and Surface Force Analysis.Frontiers in chemistry · 2021Article
- Single-Cell Tracking on Polymer Microarrays Reveals the Impact of Surface Chemistry onACS applied bio materials · 2020Article
- Influence of polydimethylsiloxane substrate stiffness on corneal epithelial cells.Royal Society open science · 2019Article
- Bioinspired Photocatalytic Shark-Skin Surfaces with Antibacterial and Antifouling Activity via Nanoimprint Lithography.ACS applied materials & interfaces · 2018Article
- Prediction of Broad-Spectrum Pathogen Attachment to Coating Materials for Biomedical Devices.ACS applied materials & interfaces · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging from their work that has failed to find relationships between WCA and microbial and stem cell attachment within large diversity material libraries and compare with the literature concluding that such simple rules are (unfortunately) wholly inadequate to explain cell-material interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.