Evidence map›Paper›PMID 28683417›Full record

ArticleGait & posture2017

Gait deficiencies associated with peripheral artery disease are different than chronic obstructive pulmonary disease.

John D McCamley, Eric J Pisciotta, Jennifer M Yentes, Shane R Wurdeman, Stephen I Rennard, Iraklis I Pipinos, Jason M Johanning, Sara A Myers

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gait & posture, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Updated Perspectives on the Role of Biomechanics in COPD: Considerations for the Clinician.International journal of chronic obstructive pulmonary disease · 2022
    Review
  9. Patient perspectives of ankle-foot orthoses for walking ability in peripheral artery disease: A qualitative study.Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

John D McCamleyCenter for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE, USA.
Eric J PisciottaCenter for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE, USA.
Jennifer M YentesCenter for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE, USA.
Shane R WurdemanCenter for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE, USA; Hanger Inc, Houston, TX, USA.
Stephen I RennardDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of Nebraska Medical Center, Omaha, NE, USA; Clinical Discovery Unit, AstraZeneca, Cambridge, UK.
Iraklis I PipinosDepartment of Surgery, Omaha Veterans' Affairs Medical Center, Omaha, NE, USA; College of Medicine, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.
Jason M JohanningDepartment of Surgery, Omaha Veterans' Affairs Medical Center, Omaha, NE, USA; College of Medicine, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.
Sara A MyersCenter for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE, USA; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: samyers@unomaha.edu.
University of Nebraska at Omaha · USUniversity of Nebraska Medical Center · US

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PHILIBERT, INGRID · 2016 to 2025
$42.8M
Visual control of locomotion in people with Parkinsons diseaseP20GM109090 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI DOTOV, DOBROMIR · 2014 to 2023
$20.5M
Mitochondrial dysfunction, oxidative damage and inflammation in claudicationR01AG034995 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PIPINOS, IRAKLIS ILIAS · 2010 to 2014
$5.2M
Improving mobility in peripheral artery disease using an ankle foot orthosisR01HD090333 · NICHD · UNIVERSITY OF NEBRASKA OMAHA · PI MYERS, SARA A · 2016 to 2020
$2.1M
Gait after intervention trial in peripheral arterial diseaseI01RX000604 · VA · OMAHA VA MEDICAL CENTER · PI JOHANNING, JASON MICHAEL · 2015 to 2016
–
NIA NIH HHS R01 AG034995NICHD NIH HHS R01 HD090333NIGMS NIH HHS P20 GM109090NIGMS NIH HHS U54 GM115458RRD VA I01 RX000604
6 · The paper itself

Abstract

objectivePrevious studies have indicated that patients with peripheral artery disease (PAD), display significant differences in their kinetic and kinematic gait characteristics when compared to healthy, aged-matched controls. The ability of patients with chronic obstructive pulmonary disease (COPD) to ambulate is also limited. These limitations are likely due to pathology-driven muscle morphology and physiology alterations establish in PAD and COP, respectively. Gait changes in PAD were compared to gait changes due to COPD to further understand how altered limb muscle due to disease can alter walking patterns. Both groups were independently compared to healthy controls. It was hypothesized that both patients with PAD and COPD would demonstrate similar differences in gait when compared to healthy controls.

methodsPatients with PAD (n=25), patients with COPD (n=16), and healthy older control subjects (n=25) performed five walking trials at self-selected speeds. Sagittal plane joint kinematic and kinetic group means were compared.

resultsPeak values for hip flexion angle, braking impulse, and propulsive impulse were significantly reduced in patients with symptomatic PAD compared to patients with COPD. After adjusting for walking velocity, significant reductions (p<0.05) in the peak values for hip flexion angle, dorsiflexor moment, ankle power generation, propulsion force, braking impulse, and propulsive impulse were found in patients with PAD compared to healthy controls. No significant differences were observed between patients with COPD and controls.

conclusionsThe results of this study demonstrate that while gait patterns are impaired for patients with PAD, this is not apparent for patients with COPD (without PAD). PAD (without COPD) causes changes to the muscle function of the lower limbs that affects gait even when subjects walk from a fully rested state. Altered muscle function in patients with COPD does not have a similar effect.

Indexed as

AdultAgedAnkle JointBiomechanical PhenomenaCase-Control StudiesGaitHip JointHumansKineticsMiddle AgedPeripheral Arterial DiseasePulmonary Disease, Chronic ObstructiveRange of Motion, ArticularChronic obstructive pulmonary diseaseGaitKinematicsKineticsPeripheral artery diseaseVascular disease

Identifiers

PMID28683417
PMCPMC5563974
OpenAlexW2627761737

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.