Evidence map›Paper›PMID 28683174›Full record

ReviewCA: a cancer journal for clinicians2017

The oncologic burden of hepatitis C virus infection: A clinical perspective.

Harrys A Torres, Terri Lynn Shigle, Nassim Hammoudi, James T Link, Felipe Samaniego, Ahmed Kaseb, Vincent Mallet

Open access · diamondAbstract readReview
In one paragraph

Review in CA: a cancer journal for clinicians, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Exploring the Therapeutic Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Implementation of Universal Hepatitis C Virus Screening in a Tertiary Cancer Center.Journal of the National Comprehensive Cancer Network : JNCCN · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Antiviral therapy use and related outcomes in patients with cancer and viral infections: results from SWOG S1204.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Latent infection screening and prevalence in cancer patients born outside of Australia: a universal versus risk-based approach?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Harrys A TorresAssociate Professor, Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX.ORCID http://orcid.org/0000-0003-0814-604X
Terri Lynn ShigleClinical Pharmacy Specialist, Division of Pharmacy, Section of Clinical Pharmacy Services, The University of Texas MD Anderson Cancer Center, Houston, TX.
Nassim HammoudiGastrointestinal/Hepatology Resident, Public Assistance - Paris Hospitals (AP-HP), Hepatology Service, Cochin Port-Royal Hospital, Paris, France.
James T LinkHematology/Oncology Fellow, Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Felipe SamaniegoAssociate Professor, Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX.
Ahmed KasebAssociate Professor, Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Vincent MalletProfessor of Hepatology, Public Assistance - Paris Hospitals (AP-HP), Hepatology Service, Cochin Port-Royal Hospital, Paris Descartes University (Paris V), National Institute of Health and Medical Research (INSERM), Unit 1223, Pasteur Institute, Paris, France.
The University of Texas MD Anderson Cancer Center · USDélégation Paris 5 · FRMaternité Port Royal · FR

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
TRAINING FOR ACADEMIC ONCOLOGY/HEMATOLOGYT32CA009666 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michael Davies, Courtney DiNardo · 1994 to 2026
$9.8M
NCI NIH HHS P30 CA016672NCI NIH HHS T32 CA009666
6 · The paper itself

Abstract

Answer questions and earn CME/CNE Chronic hepatitis C virus (HCV) infection affects millions of people worldwide and is associated with cancer. Direct-acting antivirals (DAAs) have changed HCV treatment paradigms, but little is known about the management of HCV infection in patients with cancer. The substantial burden of HCV infection and the inconclusive evidence regarding its detection and management in patients with cancer prompted the authors to review the literature and formulate recommendations. Patients for whom HCV screening is recommended included all patients with hematologic malignancies, hematopoietic cell transplantation candidates, and patients with liver cancer. There is a lack of consensus-based recommendations for the identification of HCV-infected patients with other types of cancer, but physicians may at least consider screening patients who belong to groups at heightened risk of HCV infection, including those born during 1945 through 1965 and those at high risk for infection. Patients with evidence of HCV infection should be assessed by an expert to evaluate liver disease severity, comorbidities associated with HCV infection, and treatment opportunities. DAA therapy should be tailored on the basis of patient prognosis, type of cancer, cancer treatment plan, and hepatic and virologic parameters. HCV-infected patients with cancer who have cirrhosis (or even advanced fibrosis) and those at risk for liver disease progression, especially patients with HCV-associated comorbidities, should have ongoing follow-up, regardless of whether there is a sustained virologic response, to ensure timely detection and treatment of hepatocellular carcinoma. HCV infection and its treatment should not be considered contraindications to cancer treatment and should not delay the initiation of an urgent cancer therapy. CA Cancer J Clin 2017. © 2017 American Cancer Society. CA Cancer J Clin 2017;67:411-431. © 2017 American Cancer Society.

Indexed as

Hepatitis C, ChronicAntiviral AgentsHumansLiver NeoplasmsAntiviral Agentscancerdirect-acting antiviralhepatitis C virus (HCV)hepatocellular carcinomanon-Hodgkin lymphomaprimary liver cancer

Identifiers

PMID28683174
PMCPMC5591069
OpenAlexW2732983362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.