Evidence map›Paper›PMID 28683072›Full record

ArticlePloS one2017

Volume versus surface-based cortical thickness measurements: A comparative study with healthy controls and multiple sclerosis patients.

R Righart, P Schmidt, R Dahnke, V Biberacher, A Beer, D Buck, B Hemmer, J S Kirschke, C Zimmer, C Gaser and 1 more

Abstract readComparative Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Post mortem cadaveric and imaging mapping analysis of the influence of cochlear implants on cMRI assessment regarding implant positioning and artifact formation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  14. Individual differences in brain structure and self-reported empathy in children.Cognitive, affective & behavioral neuroscience · 2022
    Article
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  17. Advantages of Using Both Voxel- and Surface-based Morphometry in Cortical Morphology Analysis: A Review of Various Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

R RighartDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.ORCID http://orcid.org/0000-0001-5044-9939
P SchmidtDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
R DahnkeDepartment of Psychiatry and Department of Neurology, Jena University Hospital, Jena, Germany.
V BiberacherDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
A BeerDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
D BuckDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
B HemmerDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
J S KirschkeDepartment of Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
C ZimmerDepartment of Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
C GaserDepartment of Psychiatry and Department of Neurology, Jena University Hospital, Jena, Germany.
M MühlauDepartment of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebral cortex is a highly folded outer layer of grey matter tissue that plays a key role in cognitive functions. In part, alterations of the cortex during development and disease can be captured by measuring the cortical thickness across the whole brain. Available software tools differ with regard to labor intensity and computational demands. In this study, we compared the computational anatomy toolbox (CAT), a recently proposed volume-based tool, with the well-established surface-based tool FreeSurfer. We observed that overall thickness measures were highly inter-correlated, although thickness estimates were systematically lower in CAT than in FreeSurfer. Comparison of multiple sclerosis (MS) patients with age-matched healthy control subjects showed highly comparable clusters of MS-related thinning for both methods. Likewise, both methods yielded comparable clusters of age-related cortical thinning, although correlations between age and average cortical thickness were stronger for FreeSurfer. Our data suggest that, for the analysis of cortical thickness, the volume-based CAT tool can be regarded a considerable alternative to the well-established surface-based FreeSurfer tool.

Indexed as

SoftwareAdultAge FactorsCase-Control StudiesCerebral CortexFemaleGray MatterHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMultiple Sclerosis

Identifiers

PMID28683072
PMCPMC5500013

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.