Evidence map›Paper›PMID 28682737›Full record

ArticleQualitative health research2017

Qualitative Comparison of Barriers to Antiretroviral Medication Adherence Among Perinatally and Behaviorally HIV-Infected Youth.

Errol L Fields, Laura M Bogart, Idia B Thurston, Caroline H Hu, Margie R Skeer, Steven A Safren, Matthew J Mimiaga

Abstract read
In one paragraph

Article in Qualitative health research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  12. Qualitative Interviews to Add Patient Perspectives in Colorectal Cancer Screening: Improvements in a Learning Health System.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024
    Article
  13. Retention and Viral Suppression Among Adolescents Newly Initiating Antiretroviral Therapy in Adult HIV Care in Lima, Peru: A Retrospective Cohort Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Article
  14. Article
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  16. Patient preferences and health state utilities associated with the treatment process of antiretroviral therapy for people living with HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Errol L Fields1 Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Laura M Bogart2 RAND Corporation, Santa Monica, California, USA.
Idia B Thurston3 University of Memphis, Memphis, Tennessee, USA.
Caroline H Hu4 University of Minnesota, Minneapolis, Minnesota, USA.
Margie R Skeer5 Fenway Health, Boston, Massachusetts, USA.
Steven A Safren7 University of Miami, Coral Gables, Florida, USA.
Matthew J Mimiaga5 Fenway Health, Boston, Massachusetts, USA.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Adolescent Health Training ProgramT32HD052459 · NICHD · JOHNS HOPKINS UNIVERSITY · PI MARIA E. TRENT · 2006 to 2026
$4.0M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Addressing psychosocial comorbidities in HIV treatment and preventionK24MH094214 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2011 to 2015
$858k
NIAID NIH HHS P30 AI060354NICHD NIH HHS T32 HD052459NIDA NIH HHS K24 DA040489NIMH NIH HHS K24 MH094214
6 · The paper itself

Abstract

Medication adherence among youth living with HIV (28%-69%) is often insufficient for viral suppression. The psychosocial context of adherence barriers is complex. We sought to qualitatively understand adherence barriers among behaviorally infected and perinatally infected youth and develop an intervention specific to their needs. We conducted in-depth interviews with 30 youth living with HIV (aged 14-24 years) and analyzed transcripts using the constant comparative method. Barriers were influenced by clinical and psychosocial factors. Perinatally infected youth barriers included reactance, complicated regimens, HIV fatigue, and difficulty transitioning to autonomous care. Behaviorally infected youth barriers included HIV-related shame and difficulty initiating medication. Both groups reported low risk perception, medication as a reminder of HIV, and nondisclosure, but described different contexts to these common barriers. Common and unique barriers emerged for behaviorally infected and perinatally infected youth reflecting varying HIV experiences and psychosocial contexts. We developed a customizable intervention addressing identified barriers and their psychosocial antecedents.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAnti-HIV AgentsDepressionDrug Administration ScheduleDrug Therapy, CombinationFatigueFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalInterviews as TopicMaleMedication AdherenceRisk AssessmentSelf DisclosureAnti-HIV Agentsadolescentantiretroviral therapygrounded theoryHIVmedication adherenceNew Englandpsychosocial contextsemi-structured interviewsyoung adult

Identifiers

PMID28682737
PMCPMC5953432

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.