Evidence map›Paper›PMID 28681718›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016.

Sofie E Midgley, Astrid G Nielsen, Ramona Trebbien, Mille W Poulsen, Peter H Andersen, Thea K Fischer

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
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  11. Genomic and serologic characterization of enterovirus A71 brainstem encephalitis.Neurology(R) neuroimmunology & neuroinflammation · 2020
    Article
  12. Article
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  14. Severe enterovirus A71 associated hand, foot and mouth disease, Vietnam, 2018: preliminary report of an impending outbreak.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
  15. Article
  16. Article
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sofie E MidgleySection for Virus Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.
Astrid G NielsenSection for Virus Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.
Ramona TrebbienSection for Virus Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.
Mille W PoulsenSection for Virus Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.
Peter H AndersenInfectious Disease Epidemiology, Statens Serum Institut, Copenhagen, Denmark.
Thea K FischerSection for Virus Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Europe, enterovirus A71 (EV-A71) has primarily been associated with sporadic cases of neurological disease. The recent emergence of new genotypes and larger outbreaks with severely ill patients demonstrates a potential for the spread of new, highly pathogenic EV-A71 strains. Detection and characterisation of these new emerging EV variants is challenging as standard EV assays may not be adequate, necessitating the use of whole genome analysis.

Indexed as

Genome, ViralWhole Genome SequencingAdolescentAdultChildChild, PreschoolDisease OutbreaksEnterovirus A, HumanEnterovirus InfectionsFecesFemaleFeverGenetic VariationGenotypeHumansInfantenterovirus, classification, Diagnostics, whole genome sequencingEV-A71WGS, NGS, next generation sequencing

Identifiers

PMID28681718
PMCPMC6518347

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.