ArticleProgress in orthodontics2017
A cross-sectional analysis of the prevalence of tooth agenesis and structural dental anomalies in association with cleft type in non-syndromic oral cleft patients.
Article in Progress in orthodontics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Association between Dental Anomalies and Orofacial Clefts: A Meta-analysis.JDR clinical and translational research · 2021Pooled it
- Next-Generation Sequencing Data and Clinical Features in Patients with Cleft Palate and Tooth Agenesis: A Systematic Literature Review.Dentistry journal · 2026Review
- Minimally Invasive Cantilever RBFPD Using a 270-Degree Veneer Abutment in a Young Cleft Patient: A Clinical Adhesive Technique.Clinical case reports · 2026Article
- Artificial Intelligence-Based McNamara Analysis of Different Types of Cleft and Non-Cleft Individuals.Maedica · 2025Article
- Prevalence of Supernumerary Teeth in Patients with Cleft lip and Palate through Orthopantomographic Analysis: A Systematic Review : Prevalence of Supernumerary Teeth in Patients with Cleft lip and Palate.Galen medical journal · 2024Review
- Subphenotypes in Non-Syndromic Orofacial Cleft Patients Based on the Tooth Agenesis Code (TAC).Children (Basel, Switzerland) · 2022Article
- Pulp enlargement in individuals born with cleft lip and palate pulp, a radiographic study from the cleft lip and palate service of paraiba, Brazil'.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Article
- Prevalence and patterns of tooth agenesis among patients aged 12-22 years: A retrospective study.Korean journal of orthodontics · 2021Article
- Article
- Enamel defects in permanent teeth of patients with cleft lip and palate: a cross-sectional study.The Journal of international medical research · 2019Article
- Nonsyndromic cleft lip and/or palate: A multicenter study of the dental anomalies involved.Journal of clinical and experimental dentistry · 2018Article
- The prevalence of dental agenesis among children with cleft lip and palate patients in Lahore, Pakistan.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate the prevalence of tooth agenesis, microdontia, and tooth malformation among non-syndromic oral cleft patients and their potential association with cleft type and gender.
methodsIntraoral records and radiographs of 154 patients (97 males and 57 females) were examined. The variables assessed were tooth agenesis, microdontia, dental malformations, and cleft types. The statistics included chi-square and Fisher's exact tests as well as logistic regression to assess any mutual effects of gender and cleft type on the dental variables.
resultsTooth agenesis occurred in 50% of the sample and microdontia in 18%. Non-statistically significant odds ratios for the association of gender and cleft type with tooth agenesis were obtained. Tooth agenesis was substantially higher at the unilateral right CL + P and the bilateral CL + P in quadrant 1 and at the unilateral left CL + P and bilateral CL + P in quadrant 2. It was also higher, at the isolated cleft palate (CP) in quadrants 3 and 4. These results were attributed to teeth 22 (31.8%) and 12 (21.6%) in the maxilla and to teeth 35 (6.1%) and 45 (5.4%) in the mandible. In unilateral CL + P patients, the cleft quadrant that presented tooth agenesis was associated with the side of the cleft.
conclusionsInterdisciplinary treatment of the oral cleft patients should take into consideration the high prevalence of tooth agenesis and their association with the different cleft types. The most frequently affected teeth by cleft are by far the upper lateral incisors. Results indicate that tooth agenesis appears to be a genetically controlled anomaly related to the orofacial cleft development through various genetic links and not caused by the cleft disruptive process.
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Registered trials
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