Evidence map›Paper›PMID 28681084›Full record

ArticleLasers in medical science2017

Photobiomodulation therapy action in wound repair skin induced in aged rats old: time course of biomarkers inflammatory and repair.

Franciane Barbieri Fiorio, Solange Almeida Dos Santos, Caroline Sobral de Melo Rambo, Camila Guerra Dalbosco, Andrey Jorge Serra, Brunno Lemes de Melo, Ernesto Cesar Pinto Leal-Junior, Paulo de Tarso Camillo de Carvalho

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Franciane Barbieri FiorioPostgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Solange Almeida Dos SantosPostgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Caroline Sobral de Melo RamboPostgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Camila Guerra DalboscoHealth Sciences Center, Chapecó University (UNOCHAPECÓ), Chapecó, SC, Brazil.
Andrey Jorge SerraPostgraduate Program in Biophotonics Applied to Health Sciences, Nove de Julho University (UNINOVE), Rua Vergueiro 235, São Paulo, SP, Brazil.
Brunno Lemes de MeloPostgraduate Program in Medicine (Cardiology), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Ernesto Cesar Pinto Leal-JuniorPostgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.
Paulo de Tarso Camillo de CarvalhoPostgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil. paulo.tarso@uninove.br.
Universidade Nove de Julho · BRCommunity University of Chapecó Region - Unochapecó · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have discussed an inverse correlation between age and wound healing, because it relates to the association of aging with a gradual decrease in healing capacity. Treatment with photobiomodulation therapy (PBMT) improves wound healing by inducing increases in mitotic activity, numbers of fibroblasts, collagen synthesis, and neovascularization. Therefore, this study aimed to evaluate the effects of PBMT in cutaneous wound healing in aged rats. A punch biopsy of 8 mm in diameter was performed to produce a skin wound. The study included 45 male rats, of which 15 were young (30 days) and 30 were elderly (500 days). The 45 animals were distributed into 3 experimental groups, which were subjected to skin wounds and 1 aged group received PBMT, with a 30-mW laser beam (power density of 1.07 W/cm

Indexed as

AgingAnimalsBiomarkersChemokine CXCL1Collagen Type IInflammationInterleukin-6Low-Level Light TherapyMaleMatrix Metalloproteinase 3Matrix Metalloproteinase 9Rats, WistarRNA, MessengerSkinTime FactorsTissue Inhibitor of Metalloproteinase-2BiomarkersChemokine CXCL1Collagen Type ICxcl1 protein, ratInterleukin-6Matrix Metalloproteinase 3Matrix Metalloproteinase 9RNA, MessengerTissue Inhibitor of Metalloproteinase-2Vascular Endothelial Growth Factor AAgeInflammatory mediatorsPhotobiomodulation therapyWound healing

Identifiers

PMID28681084
OpenAlexW2730984137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.