Evidence map›Paper›PMID 28680878›Full record

ArticleFrontiers in cell and developmental biology2017

At Term, XmO and XpO Mouse Placentas Show Differences in Glucose Metabolism in the Trophectoderm-Derived Outer Zone.

Nannan He, Shujing J Lim, Joana C Moreira de Mello, Injerreau Navarro, Monika Bialecka, Daniela C F Salvatori, Lucette A J van der Westerlaken, Lygia V Pereira, Susana M Chuva de Sousa Lopes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Nannan HeDepartment of Anatomy and Embryology, Leiden University Medical CenterLeiden, Netherlands.
Shujing J LimDepartment of Anatomy and Embryology, Leiden University Medical CenterLeiden, Netherlands.
Joana C Moreira de MelloDepartment of Genetics and Evolutionary Biology, University of São PauloSão Paulo, Brazil.
Injerreau NavarroDepartment of Anatomy and Embryology, Leiden University Medical CenterLeiden, Netherlands.
Monika BialeckaDepartment of Anatomy and Embryology, Leiden University Medical CenterLeiden, Netherlands.
Daniela C F SalvatoriDepartment of Anatomy and Embryology, Leiden University Medical CenterLeiden, Netherlands.
Lucette A J van der WesterlakenDepartment of Gynaecology, Leiden University Medical CenterLeiden, Netherlands.
Lygia V PereiraDepartment of Genetics and Evolutionary Biology, University of São PauloSão Paulo, Brazil.
Susana M Chuva de Sousa LopesDepartment of Anatomy and Embryology, Leiden University Medical CenterLeiden, Netherlands.
Leiden University Medical Center · NLUniversidade de São Paulo · BRGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic mouse model (39,XO) for human Turner Syndrome (45,XO) harboring either a single maternally inherited (Xm) or paternally inherited (Xp) chromosome show a pronounced difference in survival rate at term. However, a detailed comparison of XmO and XpO placentas to explain this difference is lacking. We aimed to investigate the morphological and molecular differences between XmO and XpO term mouse placentas. We observed that XpO placentas at term contained a significantly larger area of glycogen cells (GCs) in their outer zone, compared to XmO, XX, and XY placentas. In addition, the outer zone of XpO placentas showed higher expression levels of lactate dehydrogenase (

Indexed as

glucose metabolismmouseplacentatrophoblast cellsTurner SyndromeX chromosome

Identifiers

PMID28680878
PMCPMC5478694
OpenAlexW2646395944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.