ReviewClinical and translational imaging2017
Amino acid PET and MR perfusion imaging in brain tumours.
Review in Clinical and translational imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 61 citations in OpenAlex.
- Imaging Biomarkers in Radiotherapy.Cancers · 2026Review
- Coexistence of histologically distinct intracranial tumors: Case series, literature review, and meta-analysis.Surgical neurology international · 2026Review
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- Optimization and comparison of [American journal of nuclear medicine and molecular imaging · 2025Article
- Assessment of Brain Tumour Perfusion Using Early-PhaseMolecular imaging and biology · 2024Article
- Review
- Review
- The complementary role of MRI and FET PET in high-grade gliomas to differentiate recurrence from radionecrosis.Frontiers in nuclear medicine · 2023Article
- A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Tumefactive multiple sclerosis versus high grade glioma: A diagnostic dilemma.Surgical neurology international · 2022Article
- Current emerging MRI tools for radionecrosis and pseudoprogression diagnosis.Current opinion in oncology · 2021Review
- Simultaneously acquired PET and ASL imaging biomarkers may be helpful in differentiating progression from pseudo-progression in treated gliomas.European radiology · 2021Article
- Long-term metabolic evolution of brain metastases with suspected radiation necrosis following stereotactic radiosurgery: longitudinal assessment by F-DOPA PET.Neuro-oncology · 2021Article
- Observational
- Review
- Advanced imaging techniques for neuro-oncologic tumor diagnosis, with an emphasis on PET-MRI imaging of malignant brain tumors.Current oncology reports · 2021Review
- Tumefactive multiple sclerosis versus high-grade glioma: A diagnostic dilemma.Surgical neurology international · 2021Article
- Applications of radiomics and machine learning for radiotherapy of malignant brain tumors.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020Review
- Differentiation of suprasellar meningiomas from non-functioning pituitary macroadenomas byBMC cancer · 2020Article
- PET imaging of medulloblastoma with anScientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDespite the excellent capacity of the conventional MRI to image brain tumours, problems remain in answering a number of critical diagnostic questions. To overcome these diagnostic shortcomings, PET using radiolabeled amino acids and perfusion-weighted imaging (PWI) are currently under clinical evaluation. The role of amino acid PET and PWI in different diagnostic challenges in brain tumours is controversial.
methodsBased on the literature and experience of our centres in correlative imaging with PWI and PET using
resultsPWI is more readily available, but requires substantial expertise and is more sensitive to artifacts than amino acid PET. At initial diagnosis, PWI and amino acid PET can help to define a site for biopsy but amino acid PET appears to be more powerful to define the tumor extent. Both methods are helpful to differentiate progression or recurrence from unspecific posttherapeutic changes. Assessment of therapeutic efficacy can be achieved especially with amino acid PET, while the data with PWI are sparse.
conclusionBoth PWI and amino acid PET add valuable diagnostic information to the conventional MRI in the assessment of patients with brain tumours, but further studies are necessary to explore the complementary nature of these two methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.