Evidence map›Paper›PMID 28680839›Full record

ArticleJournal of translational internal medicine2017

Early Detection of Liver Damage in Mexican Patients with Chronic Liver Disease.

Rafael Torres-Valadez, Sonia Roman, Alexis Jose-Abrego, Maricruz Sepulveda-Villegas, Claudia Ojeda-Granados, Ingrid Rivera-Iñiguez, Arturo Panduro

Open access · hybridAbstract read
In one paragraph

Article in Journal of translational internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rafael Torres-ValadezDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Sonia RomanDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Alexis Jose-AbregoDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Maricruz Sepulveda-VillegasDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Claudia Ojeda-GranadosDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Ingrid Rivera-IñiguezDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Arturo PanduroDepartment of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco, Mexico.
Universidad de Guadalajara · MXHospital Civil de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveLiver cirrhosis is usually detected at the later stages of disease. This study is aimed to detect liver damage in patients with chronic liver disease using transitional elastography (TE) and to assess the biochemical parameters associated with liver damage.

methodsIn 578 patients, chronic liver disease based on etiology was diagnosed by clinical and laboratory tests. Liver damage was evaluated with TE (FibroScan®), while its association with biochemical parameters was performed using the logistic regression tests.

resultsOverall, the main etiologies of liver damage were hepatitis C virus (HCV) (37%), alcoholic liver disease (ALD) (33%) and non-alcoholic steatohepatitis (NASH) (26%). Patients were 40 to 50 years of age. ALD and hepatitis B prevailed in men, whereas HCV and NASH in women. The stages of fibrosis were F0 (

conclusionAsymptomatic liver disease due to HCV, ALD and NASH prevailed in young adults. Advanced liver damage assessed by TE was associated with five biochemical parameters. In conjunction, both methodologies may be useful for the early detection of fibrosis and cirrhosis in Latin America.

Indexed as

chronic liver diseasecirrhosisliver fibrosisrisk factorstransient elastography

Identifiers

PMID28680839
PMCPMC5490962
OpenAlexW2607225699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.