Evidence map›Paper›PMID 28680830›Full record

ArticleTranslational cancer research2016

Harnessing protein kinase A activation to induce mesenchymal-epithelial programs to eliminate chemoresistant, tumor-initiating breast cancer cells.

Alex J Gooding, William P Schiemann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Regulating cellular cyclic adenosine monophosphate: "Sources," "sinks," and now, "tunable valves".Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alex J GoodingCase Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.
William P SchiemannCase Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Integrin-Mediated Regulation of TGF-Beta Signaling and TumorigenesisR01CA129359 · NCI · UNIVERSITY OF COLORADO DENVER · PI SCHIEMANN, WILLIAM · 2007 to 2016
$2.9M
Image-guided EMT inhibition for treating metastatic breast cancerR01CA194518 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LU, ZHENG-RONG, SCHIEMANN, WILLIAM · 2015 to 2019
$2.4M
c-Abl-mediated Suppression of Breast Cancer Development and MetastasisR01CA177069 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI SCHIEMANN, WILLIAM · 2013 to 2018
$1.7M
BORG: Role for a Novel lncRNA in Mediating Breast Cancer Metastasis and DormancyF30CA203233 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GOODING, ALEX JOSEPH · 2016 to 2019
$197k
NCI NIH HHS F30 CA203233NCI NIH HHS R01 CA129359NCI NIH HHS R01 CA177069NCI NIH HHS R01 CA194518NIGMS NIH HHS T32 GM007250
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast Cancer MetastasisChemoresistanceMesenchymal-epithelial transitionMetastasisProtein Kinase ATumor-initiating cell

Identifiers

PMID28680830
PMCPMC5495186

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.