Evidence map›Paper›PMID 28680809›Full record

ArticleFEBS open bio2017

Antimicrobial ceragenins inhibit biofilms and affect mammalian cell viability and migration

Melissa A Olekson, Tao You, Paul B Savage, Kai P Leung

Abstract read
In one paragraph

Article in FEBS open bio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  17. Article
  18. Antibacterial and Antibiofilm Activities of Ceragenins againstTurkish journal of pharmaceutical sciences · 2019
    Article
  19. Article
  20. Susceptibility of Multidrug-Resistant Bacteria, Isolated from Water and Plants in Nigeria, to Ceragenins.International journal of environmental research and public health · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melissa A OleksonDental and Craniofacial Trauma Research & Tissue Regeneration Directorate United States Army Institute of Surgical Research JBSA Fort Sam Houston TX USA.
Tao YouDental and Craniofacial Trauma Research & Tissue Regeneration Directorate United States Army Institute of Surgical Research JBSA Fort Sam Houston TX USA.
Paul B SavageDepartment of Chemistry and Biochemistry Brigham Young University Provo UT USA.
Kai P LeungDental and Craniofacial Trauma Research & Tissue Regeneration Directorate United States Army Institute of Surgical Research JBSA Fort Sam Houston TX USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The healing of burn wounds is often hampered by bacterial infection and the formation of biofilms. Antimicrobial peptides (AMPs) are effective in promoting wound healing, but are susceptible to degradation. We have tested the ability of ceragenins (CSAs), mimics of antimicrobial peptides, to mitigate preformed biofilms and stimulate wound healing

Indexed as

antimicrobialsbiofilmswound healing

Identifiers

PMID28680809
PMCPMC5494304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.