Evidence map›Paper›PMID 28680805›Full record

ArticleFEBS open bio2017

miR-944 inhibits metastasis of gastric cancer by preventing the epithelial-mesenchymal transition via MACC1/Met/AKT signaling.

Tao Pan, Wenjun Chen, Xiaoming Yuan, Jun Shen, Chuan Qin, Linbo Wang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in FEBS open bio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tao PanDepartment of Surgical Oncology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China.
Wenjun ChenDepartment of Surgical Oncology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China.
Xiaoming YuanDepartment of Surgical Oncology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China.
Jun ShenDepartment of Surgical Oncology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China.
Chuan QinDepartment of Surgical Oncology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China.
Linbo WangDepartment of Surgical Oncology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China.
Sir Run Run Shaw Hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are reported to play vital roles in tumor progression. Recently, miR-944 was reported to play either an oncogenic or tumor suppressive role in human cancers. However, the expression of miR-944 and its exact role in gastric cancer (GC) remain unknown. This study aimed to evaluate whether loss of miR-944 could promote the epithelial-mesenchymal transition (EMT) of GC. Reduced expression of miR-944 was identified in 40 pairs of human GC and matched normal tissues by qRT-PCR. Reduced expression of mi-944 was also observed in GC cell lines. Restoration of miR-944 inhibited cell migration and invasion in MGC-803 cells, while its loss facilitated metastasis of SGC-7901 and BGC-823 cells. Notably, miR-944 overexpression prohibited EMT of GC cells

Indexed as

EMTgastric cancerMACC1Met/AKT signalingmicroRNA‐944

Identifiers

PMID28680805
PMCPMC5494292
OpenAlexW2594511180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.