ArticleCerebellum & ataxias2017
Gray matter density loss in essential tremor: a lobule by lobule analysis of the cerebellum.
Article in Cerebellum & ataxias, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The Contribution of Neuroimaging to the Understanding of Essential Tremor Pathophysiology: a Systematic Review.Cerebellum (London, England) · 2022Pooled it
- Imaging the Pathophysiology of Essential Tremor-A Systematic Review.Frontiers in neurology · 2021Pooled it
- Voxel-based morphometry and task functional magnetic resonance imaging in essential tremor: evidence for a disrupted brain network.Scientific reports · 2020Trial
- Brain Imaging Phenotypes Associated with Polygenic Risk for Essential Tremor.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Locus Coeruleus Degeneration in Essential Tremor With Mild Cognitive Impairment: A Neuromelanin MRI Study.CNS neuroscience & therapeutics · 2025Article
- Multimodal Magnetic Resonance Findings in Parkinson's Disease With "Antecedent Essential Tremor": A Case Series of a Large Kindred.Neuropsychiatric disease and treatment · 2025Article
- Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density.Cerebellum (London, England) · 2024Article
- Smaller Cerebellar Lobule VIIb is Associated with Tremor Severity in Parkinson's Disease.Cerebellum (London, England) · 2024Article
- Elevated serum neurofilament light chain protein in patients with essential tremor.European journal of neurology · 2024Article
- Serum Neurofilament Light-Chain Levels in Essential Tremor: A Replication Study.Neuro-degenerative diseases · 2024Article
- Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density.Research square · 2023Article
- Reproducibility of cerebellar involvement as quantified by consensus structural MRI biomarkers in advanced essential tremor.Scientific reports · 2023Article
- Postmortem Cerebellar Volume Is Not Reduced in Essential Tremor: A Comparison with Multiple System Atrophy and Controls.Journal of Parkinson's disease · 2023Article
- Cognitive impairment in essential tremor assessed by the cerebellar cognitive affective syndrome scale.Frontiers in neurology · 2023Article
- Cerebellar voxel-based morphometry in essential tremor.Journal of neurology · 2022Article
- Is essential tremor a degenerative disorder or an electric disorder? Degenerative disorder.International review of neurobiology · 2022Article
- Clinical and Kinematic Features of Valproate-Induced Tremor and Differences with Essential Tremor.Cerebellum (London, England) · 2021Article
- Impaired integrity of commissural and association fibers in essential tremor patients: Evidence from a diffusion tensor imaging studyTurkish journal of medical sciences · 2021Observational
- Voxel-Based Morphometry of Cerebellar Lobules in Essential Tremor.Frontiers in aging neuroscience · 2021Article
- Structural Correlates of the Sensorimotor Cerebellum in Parkinson's Disease and Essential Tremor.Movement disorders : official journal of the Movement Disorder Society · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe pathophysiological basis for essential tremor (ET) remains unclear, although evidence increasingly links it to a disordered and perhaps degenerative cerebellum. Prior imaging studies have treated the cerebellum
resultsWhen all ET cases and controls were compared, none of the regions met the BH FDR criteria for significance. When compared with controls, ET cases with head or jaw tremor (
conclusionsWe showed that ET cases with various forms of cranial tremor differed from controls with respect to cerebellar GM density, with evidence of GM reduction across multiple cerebellar regions. Additional work, using a lobule-by-lobule approach, is needed to confirm these results and precisely map the regional differences in ET cases, subgroups of ET cases, and controls.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.