ArticleThe journal of advanced prosthodontics2017
Characterization and antimicrobial efficacy of Portland cement impregnated with silver nanoparticles.
Article in The journal of advanced prosthodontics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed.
- Applications of Silver Nanoparticles in Dentistry.Cureus · 2023Review
- Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review.Pharmaceutics · 2023Review
- Is Silver the New Gold? A Systematic Review of the Preclinical Evidence of Its Use in Bone Substitutes as Antiseptic.Antibiotics (Basel, Switzerland) · 2022Review
- Antimicrobial Properties of Silver-Modified Denture Base Resins.Nanomaterials (Basel, Switzerland) · 2022Article
- Portland Cement: An Overview as a Root Repair Material.BioMed research international · 2022Review
- Development of Antibacterial and Antifouling Innovative and Eco-Sustainable Sol-Gel Based Materials: From Marine Areas Protection to Healthcare Applications.Gels (Basel, Switzerland) · 2021Review
- Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation.International journal of molecular sciences · 2021Review
- [Application of nanodrug carriers in the prevention and treatment of infection around orthopedic prosthesis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019Review
- Application of Antimicrobial Nanoparticles in Dentistry.Molecules (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigated the effects of silver nanoparticle (SN) loading into hydraulic calcium silicate-based Portland cement on its mechanical, antibacterial behavior and biocompatibility as a novel dental bone substitute. MATERIALS AND
methodsChemically reduced colloidal SN were combined with Portland cement (PC) by the concentrations of 0 (control), 1.0, 3.0, and 5.0 wt%. The physico-mechanical properties of silver-Portland cement nanocomposites (SPNC) were investigated through X-ray diffraction (XRD), setting time, compressive strength, solubility, and silver ion elution. Antimicrobial properties of SPNC were tested by agar diffusion against
resultsXRD certified that SN was successfully impregnated in PC. SPNC at above 3.0 wt% significantly reduced both initial and final setting times compared to control PC. No statistical differences of the compressive strength values were detected after SN loadings, and solubility rates of SPNC were below 3.0%, which are acceptable by ADA guidelines. Ag ion elutions from SPNC were confirmed with dose-dependence on the concentrations of SN added. SPNC of 5.0 wt% inhibited the growth of Streptococci, whereas no antimicrobial activity was shown in control PC. SPNC revealed no cytotoxic effects to HGF following ISO 10993 (cell viability > 70%).
conclusionAddition of SN promoted the antibacterial activity and favored the bio-mechanical properties of PC; thus, SPNC could be a candidate for the futuristic dental biomaterial. For clinical warrant, further studies including the inhibitory mechanism,
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