Evidence map›Paper›PMID 28680408›Full record

ReviewFrontiers in psychology2017

A Potential Role for mu-Opioids in Mediating the Positive Effects of Gratitude.

Max Henning, Glenn R Fox, Jonas Kaplan, Hanna Damasio, Antonio Damasio

Abstract readReview
In one paragraph

Review in Frontiers in psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Resilience Building Practices for Women Physicians.Journal of women's health (2002) · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Social touch and human development.Developmental cognitive neuroscience · 2019
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Max HenningPsychology, Brain and Creativity Institute, University of Southern CaliforniaLos Angeles, CA, United States.
Glenn R FoxPsychology, Brain and Creativity Institute, University of Southern CaliforniaLos Angeles, CA, United States.
Jonas KaplanPsychology, Brain and Creativity Institute, University of Southern CaliforniaLos Angeles, CA, United States.
Hanna DamasioPsychology, Brain and Creativity Institute, University of Southern CaliforniaLos Angeles, CA, United States.
Antonio DamasioPsychology, Brain and Creativity Institute, University of Southern CaliforniaLos Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gratitude is a complex emotional feeling associated with universally desirable positive effects in personal, social, and physiological domains. Why or how gratitude achieves these functional outcomes is not clear. Toward the goal of identifying its' underlying physiological processes, we recently investigated the neural correlates of gratitude. In our study, participants were exposed to gratitude-inducing stimuli, and rated each according to how much gratitude it provoked. As expected, self-reported gratitude intensity correlated with brain activity in distinct regions of the medial pre-frontal cortex associated with social reward and moral cognition. Here we draw from our data and existing literature to offer a theoretical foundation for the physiological correlates of gratitude. We propose that mu-opioid signaling (1) accompanies the mental experience of gratitude, and (2) may account for the positive effects of gratitude on social relationships, subjective wellbeing, and physiological health.

Indexed as

fMRIgratitudehealthmu-opioidsocial supportstress-relief

Identifiers

PMID28680408
PMCPMC5478726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.