Evidence map›Paper›PMID 28680346›Full record

ArticleJournal of medical biochemistry2017

Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease.

Danijela Ristovski-Kornic, Aleksandra Stefanović, Jelena Kotur-Stevuljević, Aleksandra Zeljković, Vesna Spasojević-Kalimanovska, Jelena Vekić, Milica Miljković, Dušan Paripović, Amira Peco-Antić, Zorana Jelić-Ivanović

Open access · diamondAbstract read
In one paragraph

Article in Journal of medical biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Danijela Ristovski-KornicHealth Center Pančevo, Serbia.
Aleksandra StefanovićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Jelena Kotur-StevuljevićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Aleksandra ZeljkovićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Vesna Spasojević-KalimanovskaDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Jelena VekićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Milica MiljkovićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Dušan ParipovićDepartment of Nephrology, University Children's Hospital, Belgrade, Serbia.
Amira Peco-AntićDepartment of Nephrology, University Children's Hospital, Belgrade, Serbia.
Zorana Jelić-IvanovićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
University of Belgrade · RSUniversity Children's Hospital, Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to explore oxidative stress status, especially the enzyme myeloperoxidase in children with end-stage renal disease. Also, we investigated possible associations between the atherogenic index of plasma and these parameters.

methodsLipid status parameters, oxidative stress status parameters, and myeloperoxidase concentration were measured in the sera of 20 children in the last stage of chronic renal disease (ESRD) and 35 healthy children of matching age and sex. The Atherogenic Index of Plasma (AIP) was calculated according to the appropriate equation.

resultsWe did not find any significant differences in myeloperoxidase concentrations between the investigated groups (p=0.394). Oxidative stress parameters were, however, significantly higher in the patient group (p<0.001), as well as the atherogenic index of plasma (p<0.001). Myeloperoxidase concentration and advanced oxidation protein product (AOPP) concentration were independently associated with increased AIP in the patient group (p<0.05).

conclusionsChanges in AIP in children with ERSD are associated with the oxidative stress status and myeloper-oxidase concentration.

Indexed as

chronic kidney diseasemyeloperoxidaseoxidative stress

Identifiers

PMID28680346
PMCPMC5471656
OpenAlexW2552810096

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.