ArticleEvolutionary bioinformatics online2017
Genome-Wide Identification and Comparative Analysis of Albumin Family in Vertebrates.
Article in Evolutionary bioinformatics online, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 47 citations in OpenAlex.
- The first de novo genome assembly and annotation of a green-blooded skink (Prasinohaema aff. flavipes) from a historic museum sample.The Journal of heredity · 2025Article
- Effects of Tuna By-Product Meal on Growth, Whole-Body Mercury, Phosphorus Load, and Plasma Chemistry in Juvenile Greater AmberjackAnimals : an open access journal from MDPI · 2024Article
- Peptide derivedHeliyon · 2023Article
- Variations in the Human Serum Albumin Gene: Molecular and Functional Aspects.International journal of molecular sciences · 2022Review
- Understanding the dynamics of physiological changes, protein expression, and PFAS in wildlife.Environment international · 2022Review
- Serum Albumin in Health and Disease: Esterase, Antioxidant, Transporting and Signaling Properties.International journal of molecular sciences · 2021Review
- Whole blood and blood components from vertebrates differentially affect egg formation in three species of anautogenous mosquitoes.Parasites & vectors · 2021Article
- Integrative Role of Albumin: Evolutionary, Biochemical and Pathophysiological Aspects.Journal of evolutionary biochemistry and physiology · 2021Article
- Antioxidant Potential of Mung Bean (Foods (Basel, Switzerland) · 2020Article
- Article
- Diagnosis, Phenotype, and Molecular Genetics of Congenital Analbuminemia.Frontiers in genetics · 2019Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Albumins are the most well-known globular proteins, and the most typical representatives are the serum albumins. However, less attention was paid to the albumin family, except for the human and bovine serum albumin. To characterize the features of albumin family, we have mined all the putative albumin proteins from the available genome sequences. The results showed that albumin is widely distributed in vertebrates, but not present in the bacteria and archaea. The phylogenetic analysis of vertebrate albumin family implied an evolutionary relationship between members of serum albumin, α-fetoprotein, vitamin D-binding protein, and afamin. Meanwhile, a new member from the albumin family was found, namely, extracellular matrix protein 1. The structural analysis revealed that the motifs for forming the internal disulfide bonds are highly conserved in the albumin family, despite the low overall sequence identity across the family. The domain arrangement of albumin proteins indicated that most of vertebrate albumins contain 3 characteristic domains, arising from 2 evolutionary patterns. And a significant trend has been observed that the albumin proteins in higher vertebrate species tend to possess more characteristic domains. This study has provided the fundamental information required for achieving a better understanding of the albumin distribution, phylogenetic relationship, characteristic motif, structure, and new insights into the evolutionary pattern.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.