ReviewNature reviews. Rheumatology2017
Sexual and reproductive health in rheumatic disease.
Review in Nature reviews. Rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.
- Sexual dysfunction in Behçet's syndrome.Rheumatology international · 2020Pooled it
- Astaxanthin attenuates CTX-induced premature ovarian failure by alleviating ovarian apoptosis and autophagy in vivo.Journal of ovarian research · 2026Article
- Serine inhibits granulosa cell ferroptosis to maintain ovarian function.Nature communications · 2026Article
- Immune-mediated skin diseases and erectile dysfunction: mechanisms and multidisciplinary management.Frontiers in immunology · 2026Review
- A clinical care pathway for managing pregnancy in patients with inflammatory arthritis.Clinical rheumatology · 2026Review
- From arthritis to erectile dysfunction: potential pathophysiological mechanisms and multidisciplinary integrated management.Frontiers in cell and developmental biology · 2026Review
- Fertility and infertility knowledge among physicians caring for women with rheumatic diseases is suboptimal: a cross-sectional survey.Rheumatology international · 2025Article
- Nicotinamide boosts oocyte quantity and quality by promoting N4-acetylation modification in lupus mice.Science advances · 2025Article
- Rituximab for Early-Onset Juvenile Dermatomyositis Complicated by Interstitial Lung Disease.Case reports in pediatrics · 2025Article
- Adenomyosis in patients with rheumatic diseases: a cross-disciplinary clinical observation.Frontiers in reproductive health · 2025Article
- Discussing male sexual and reproductive health in the rheumatology outpatient clinic: a Q-methodology study.BMC rheumatology · 2024Article
- An integrated approach to the treatment of Rheumatic diseases: the role of psychological interventions.Rheumatology international · 2024Review
- Ovarian reserve alteration in premenopausal women with systemic sclerosis.Rheumatology international · 2024Article
- NSAID exposure delays time-to-pregnancy in patients with spondyloarthritis: an analysis of the GR2 prospective cohort.RMD open · 2024Observational
- Uncovering the link between inflammatory rheumatic diseases and male reproductive health: a perspective on male infertility and sexual dysfunction.Rheumatology international · 2024Review
- Periconceptional Counselling in Women with Autoimmune Inflammatory Rheumatic Diseases.Journal of clinical medicine · 2024Review
- Sexual and reproductive health while living with rheumatoid arthritis: The impact of the disease stage on patient perspectives.PloS one · 2024Article
- Biopsychosocial factors are associated with impaired sexual function in Mexican patients with rheumatoid arthritis.PloS one · 2024Article
- Fertility issues in women of childbearing age with spondyloarthritis.Frontiers in immunology · 2024Review
- Reproductive Issues and Pregnancy Implications in Systemic Sclerosis.Clinical reviews in allergy & immunology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Family size is reduced among patients with rheumatic diseases. The causes for the low number of children are multifactorial and include impaired sexual function, decreased gonadal function, pregnancy loss, therapy and personal choices. Sexuality contributes to quality of life in patients with rheumatic disease, but is often ignored by health professionals. Both disease-related factors and psychological responses to chronic disease can impair sexual functioning. Toxic effects of anti-inflammatory and immunosuppressive drugs can induce transient or permanent gonadal failure in women and men. Furthermore, permanent infertility can be a consequence of treatment with cyclophosphamide, whereas transient infertility can be caused by NSAIDs in women and sulfasalazine in men. These adverse effects must be communicated to the patients, and measures to preserve fertility should be initiated before the start of gonadotoxic therapy. Management of patients of both genders should include regular family planning, effective treatment of high disease activity, sexual counselling, and, if necessary, infertility treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.