ArticleScientific reports2017
Transcranial random noise stimulation and cognitive training to improve learning and cognition of the atypically developing brain: A pilot study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Math Deficits in Children With Dyscalculia by tRNS: a Randomized, Double-blind Study
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effectiveness of transcranial electrical stimulation in individuals with specific learning disorder (SLD): systematic review and transfer analysis.Journal of neurodevelopmental disorders · 2025Pooled it
- Pooled it
- The effects of transcranial random noise stimulation on excitation/inhibition balance in ADHD.NeuroImage. Clinical · 2026Trial
- Transcranial random noise stimulation combined with cognitive training for treating ADHD: a randomized, sham-controlled clinical trial.Translational psychiatry · 2023Trial
- Performance after training in a complex cognitive task is enhanced by high-definition transcranial random noise stimulation.Scientific reports · 2022Trial
- Improvement in creativity after transcranial random noise stimulation (tRNS) over the left dorsolateral prefrontal cortex.Scientific reports · 2019Trial
- Perceptual Learning of Multiple Object Tracking Is Not Enhanced by Transcranial Random Noise Stimulation of hMT.Translational vision science & technology · 2026Article
- Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN).Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- Article
- Effects on nonverbal numerical acuity performance after a single-session transient random noise stimulation over the intraparietal sulcus or dorsolateral prefrontal cortex.Scientific reports · 2025Article
- tDCS and neurofeedback in ADHD treatment.Frontiers in systems neuroscience · 2025Review
- Short-term number sense training recapitulates long-term neurodevelopmental changes from childhood to adolescence.Developmental science · 2024Article
- Effects of online tDCS and hf-tRNS on reading performance in children and adolescents with developmental dyslexia: a study protocol for a cross sectional, within-subject, randomized, double-blind, and sham-controlled trial.Frontiers in neurology · 2024Article
- Stimulation with acoustic white noise enhances motor excitability and sensorimotor integration.Scientific reports · 2022Article
- Understanding the Effects of Transcranial Electrical Stimulation in Numerical Cognition: A Systematic Review for Clinical Translation.Journal of clinical medicine · 2022Review
- Non-invasive brain stimulation and neuroenhancement.Clinical neurophysiology practice · 2022Review
- Examining the Effect of Transcranial Electrical Stimulation and Cognitive Training on Processing Speed in Pediatric Attention Deficit Hyperactivity Disorder: A Pilot Study.Frontiers in human neuroscience · 2022Article
- Boosting Numerical Cognition in Children and Adolescents with Mathematical Learning Disabilities by a Brain-Based Intervention: A Study Protocol for a Randomized, Sham-Controlled Clinical Trial.International journal of environmental research and public health · 2021Article
- The Effect of Transcranial Random Noise Stimulation on Cognitive Training Outcome in Healthy Aging.Frontiers in neurology · 2021Article
- [Review of cognitive enhancement techniques based on the combination of cognitive training and transcranial direct current stimulation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Learning disabilities that affect about 10% of human population are linked to atypical neurodevelopment, but predominantly treated by behavioural interventions. Behavioural interventions alone have shown little efficacy, indicating limited success in modulating neuroplasticity, especially in brains with neural atypicalities. Even in healthy adults, weeks of cognitive training alone led to inconsistent generalisable training gains, or "transfer effects" to non-trained materials. Meanwhile, transcranial random noise stimulation (tRNS), a painless and more direct neuromodulation method was shown to further promote cognitive training and transfer effects in healthy adults without harmful effects. It is unknown whether tRNS on the atypically developing brain might promote greater learning and transfer outcomes than training alone. Here, we show that tRNS over the bilateral dorsolateral prefrontal cortices (dlPFCs) improved learning and performance of children with mathematical learning disabilities (MLD) during arithmetic training compared to those who received sham (placebo) tRNS. Training gains correlated positively with improvement on a standardized mathematical diagnostic test, and this effect was strengthened by tRNS. These findings mirror those in healthy adults, and encourage replications using larger cohorts. Overall, this study offers insights into the concept of combining tRNS and cognitive training for improving learning and cognition of children with learning disabilities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.