Evidence map›Paper›PMID 28680043›Full record

ArticleScientific reports2017

Molecular epidemiology of Mycobacterium bovis in Cameroon.

N F Egbe, A Muwonge, L Ndip, R F Kelly, M Sander, V Tanya, V Ngu Ngwa, I G Handel, A Novak, R Ngandalo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Insight into the genetic diversity ofMicrobiology spectrum · 2026
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  5. Article
  6. Molecular Characterisation ofCurrent issues in molecular biology · 2023
    Article
  7. Unraveling the epidemiology ofFrontiers in veterinary science · 2023
    Article
  8. Geo-epidemiology of animal tuberculosis andFrontiers in microbiology · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Microorganisms · 2020
    Review
  14. Article
  15. Article
  16. Association ofFrontiers in veterinary science · 2018
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 4 countries.

N F EgbeDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
A MuwongeDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK. adrian.muwonge@roslin.ed.ac.uk.ORCID 0000-0002-8579-0384
L NdipLaboratory for Emerging Infectious Diseases, University of Buea, Buea, Cameroon.
R F KellyDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.ORCID 0000-0003-0158-4506
M SanderTuberculosis Reference Laboratory, Bamenda, P.O. Box 586, Cameroon.
V TanyaCameroon Academy of Sciences, P.O. Box 1457, Yaoundé, Cameroon.
V Ngu NgwaSchool of Veterinary Medicine and Sciences, University of Ngaoundere, B.P. 454, Ngaoundere, Cameroon.
I G HandelDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
A NovakDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
R NgandaloLaboratoire de Recherches Vétérinaires et Zootechniques de Farcha, N'Djaména, Chad.
S MazeriDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
K L MorganInstitute of Ageing and Chronic Disease, University of Liverpool, Leahurst Campus, Neston, Wirral, CH64 7TE, UK.
A AsuquoMicrobiology and Parasitology Unit, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria.
B M de C BronsvoortDivision of Genetics and Genomics, The Roslin Institute and the Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.ORCID 0000-0002-3271-8485
Roslin Institute · GBCameroon Academy of Sciences · CMLaboratoire de Recherches Vétérinaires et Zootechniques de Farcha · TDUniversity of Bamenda · CMUniversity of Buea · CMUniversity of Calabar · NGUniversity of Liverpool · GBUniversity of Ngaoundéré · CM

Funding

Wellcome Trust
6 · The paper itself

Abstract

We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201 and 179 cattle with and without bTB-like lesions respectively out of 2,346 cattle slaughtered at Bamenda, Ngaoundere, Garoua and Maroua abattoirs between 2012-2013. Two hundred and fifty-five M. bovis were isolated, identified and genotyped using deletion analysis, Hain® Genotype MTBC, spoligotyping and MIRU-VNTR. African 1 was the dominant M. bovis clonal complex, with 97 unique genotypes including 19 novel spoligotypes representing the highest M. bovis genetic diversity observed in Africa to date. SB0944 and SB0953 dominated (63%) the observed spoligotypes. A third of animals with multiple lesions had multiple strain infections. Higher diversity but little evidence of recent transmission of M. bovis was more common in Adamawa compared to the North-West Region. The Adamawa was characterised by a high frequency of singletons possibly due to constant additions from an active livestock movement network compared to the North-West Region where a local expansion was more evident. The latter combined with population-based inferences suggest an unstable and stable bTB-endemic status in the North-West and Adamawa Regions respectively.

Indexed as

AnimalsBacterial Typing TechniquesCameroonCattleFemaleGenetic VariationMaleMolecular EpidemiologyMolecular TypingMycobacterium bovisPhylogenyTuberculosis, Bovine

Identifiers

PMID28680043
PMCPMC5498612
OpenAlexW2728004513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.