Evidence map›Paper›PMID 28680009›Full record

ReviewFukushima journal of medical science2017

Contrast-enhanced harmonic endoscopic ultrasonography in gallbladder cancer and pancreatic cancer.

Mitsuru Sugimoto, Tadayuki Takagi, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Ko Watanabe, Jun Nakamura, Hitomi Kikuchi, Yuichi Waragai, Mika Takasumi and 3 more

Open access · diamondAbstract readReview
In one paragraph

Review in Fukushima journal of medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Gallbladder neuroendocrine neoplasms: a review.Abdominal radiology (New York) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Mitsuru SugimotoDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Tadayuki TakagiDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Rei SuzukiDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Naoki KonnoDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Hiroyuki AsamaDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Ko WatanabeDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Jun NakamuraDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Hitomi KikuchiDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Yuichi WaragaiDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Mika TakasumiDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Yuki SatoDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Takuto HikichiDepartment of Endoscopy, Fukushima Medical University Hospital.
Hiromasa OhiraDepartment of Gastroenterology, Fukushima Medical University, School of Medicine.
Fukushima Medical University · JPFukushima Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic ultrasonography (EUS) plays a major role in diagnosing gallbladder (GB) cancer and pancreatic cancer (PC). In cases of GB cancer, EUS allows for precise observations of morphology and wall layers. However, proficiency is required for the morphologic diagnosis of GB tumors. Therefore, contrast-enhanced harmonic EUS (CH-EUS) began to be performed to diagnose GB lesions. CH-EUS enables real-time observation of the hemodynamics of GB tumors. The enhanced patterns generated by CH-EUS improve precision in the diagnosis of such tumors.PC appears as a hypoechoic mass on EUS. However, distinguishing between PC and mass-forming pancreatitis or focal autoimmune pancreatitis (AIP) is difficult via conventional EUS. CH-EUS allows for differentiating among these diseases (PC is hypoenhanced and heterogeneously enhanced, pancreatitis is isoenhanced, and a pancreatic neuroendocrine tumor is hyperenhanced). EUS-guided fine needle aspiration (EUS-FNA) also contributes to pathological diagnoses of pancreatic lesions. However, certain PC patients cannot be diagnosed via EUS-FNA. PC is heterogeneously enhanced on CH-EUS, and unenhanced regions have been reported to be areas of fibrosis or necrosis. CH-EUS-guided fine needle aspiration (CH-EUS-FNA) permits puncturing of the enhanced area while avoiding necrotic and fibrotic regions. Moreover, as CH-EUS findings have been quantitatively analyzed, a time-intensity curve (TIC) has become usable for diagnosing solid pancreatic lesions. CH-EUS-related techniques have been developed and increasingly utilized in the pancreaticobiliary area.

Indexed as

Contrast MediaEndosonographyImage EnhancementEndoscopic Ultrasound-Guided Fine Needle AspirationGallbladder NeoplasmsHumansPancreatic NeoplasmsContrast Media

Identifiers

PMID28680009
PMCPMC5597522
OpenAlexW2729964260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.