Evidence map›Paper›PMID 28679769›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral

Ming Li, Laszlo Radvanyi, Bingnan Yin, Kiera Rycaj, Jia Li, Raghavender Chivukula, Kevin Lin, Yue Lu, JianJun Shen, David Z Chang and 3 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 94 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 3 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. HERV-K TM Subunit Elicits CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
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  17. Article
  18. Review
  19. Article
  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Ming LiViral Oncology Program, Center for Cancer and Metabolism, SRI International, Menlo Park, California.
Laszlo RadvanyiEMD Serono Research and Development Institute, Billerica, Massachusetts.
Bingnan YinDepartment of Inflammation and Epigenetics, Methodist Research Institute, Houston, Texas.
Kiera Rycaj
Jia LiViral Oncology Program, Center for Cancer and Metabolism, SRI International, Menlo Park, California.
Raghavender ChivukulaViral Oncology Program, Center for Cancer and Metabolism, SRI International, Menlo Park, California.
Kevin LinDepartment of Epigenetics and Molecular Carcinogenesis, Science Park, the University of Texas MD Anderson Cancer Center, Smithville, Texas.
Yue LuDepartment of Epigenetics and Molecular Carcinogenesis, Science Park, the University of Texas MD Anderson Cancer Center, Smithville, Texas.
JianJun ShenDepartment of Epigenetics and Molecular Carcinogenesis, Science Park, the University of Texas MD Anderson Cancer Center, Smithville, Texas.
David Z ChangVirginia Oncology Associates, Newport News, Virginia.
Donghui LiDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Gary L JohanningViral Oncology Program, Center for Cancer and Metabolism, SRI International, Menlo Park, California.
Feng Wang-JohanningViral Oncology Program, Center for Cancer and Metabolism, SRI International, Menlo Park, California. feng.wang-johanning@sri.com.
SRI International · USThe University of Texas MD Anderson Cancer Center · USHouston Methodist · USMerck Serono (Italy) · ITVirginia Oncology Associates · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarcinogenesisCell Line, TumorCell ProliferationEndogenous RetrovirusesGene Expression Regulation, NeoplasticGene Expression Regulation, ViralGene Knockdown TechniquesHost-Pathogen InteractionsHumansPancreatic NeoplasmsRecombinant Fusion ProteinsRNA, Small InterferingSignal TransductionViral Envelope ProteinsRecombinant Fusion ProteinsRNA, Small InterferingViral Envelope Proteins

Identifiers

PMID28679769
PMCPMC5777511
OpenAlexW2729218605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.