SynthesisBMJ open2017
Risk of recurrent spontaneous preterm birth: a systematic review and meta-analysis.
Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 8 syntheses or guidelines pooled it, 175 citations in OpenAlex.
- Does vaginal progesterone prevent recurrent preterm birth in women with a singleton gestation and a history of spontaneous preterm birth? Evidence from a systematic review and meta-analysis.American journal of obstetrics and gynecology · 2022Pooled it
- Is there a maternal blood biomarker that can predict spontaneous preterm birth prior to labour onset? A systematic review.PloS one · 2022Pooled it
- A systematic review and meta-analysis of obstetric and maternal outcomes after prior uterine artery embolization.Scientific reports · 2021Pooled it
- Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- Cervical length varies considering different populations and gestational outcomes: Results from a systematic review and meta-analysis.PloS one · 2021Pooled it
- Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis.BMC pregnancy and childbirth · 2020Pooled it
- Determinants of preterm birth among mothers who gave birth in East Africa: systematic review and meta-analysis.Italian journal of pediatrics · 2020Pooled it
- Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis.American journal of obstetrics and gynecology · 2018Pooled it
- Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT.Health technology assessment (Winchester, England) · 2024Trial
- Effect of home-based childcare on childhood mortality in rural Maharashtra, India: a cluster randomised controlled trial.BMJ global health · 2022Trial
- Evaluation of low-dose aspirin in the prevention of recurrent spontaneous preterm labour (the APRIL study): A multicentre, randomised, double-blinded, placebo-controlled trial.PLoS medicine · 2022Trial
- Induction of labor with Foley catheter and risk of subsequent preterm birth: follow-up study of two randomized controlled trials (PROBAAT-1 and -2).Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2021Trial
- Risk of recurrent spontaneous preterm birth among those with persistent cervical HPV infection.Research square · 2026Article
- Unpacking Preterm Birth: How Granular Epidemiologic Analyses Can Inform Interventions.Paediatric and perinatal epidemiology · 2026Article
- Disparities in Patterns of Preterm and Early Term Second Births Among Non-Hispanic Black and White Mothers.Paediatric and perinatal epidemiology · 2026Article
- Variation in risk factors and timing of birth for different types of preterm birth: A historical cohort study.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Usefulness of glycated albumin levels in predicting the maternal or neonatal complications of gestational diabetes mellitus during late pregnancy in South Korea: a retrospective study.Korean journal of family medicine · 2025Article
- Preterm delivery is a risk factor for intrapartum complications in a subsequent term delivery.BMC pregnancy and childbirth · 2025Article
- Impact of Obstetric History on Preterm Birth: An Observational Study at a Tertiary Care Hospital in North India.Cureus · 2025Article
- Organ-on-a-Chip Models of the Female Reproductive System: Current Progress and Future Perspectives.Micromachines · 2025Review
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine the risk of recurrent spontaneous preterm birth (sPTB) following sPTB in singleton pregnancies.
designSystematic review and meta-analysis using random effects models. DATA SOURCES: An electronic literature search was conducted in OVID Medline (1948-2017), Embase (1980-2017) and ClinicalTrials.gov (completed studies effective 2017), supplemented by hand-searching bibliographies of included studies, to find all studies with original data concerning recurrent sPTB. STUDY ELIGIBILITY CRITERIA: Studies had to include women with at least one spontaneous preterm singleton live birth (<37 weeks) and at least one subsequent pregnancy resulting in a singleton live birth. The Newcastle-Ottawa Scale was used to assess study quality.
resultsOverall, 32 articles involving 55 197 women, met all inclusion criteria. Generally studies were well conducted and had a low risk of bias. The absolute risk of recurrent sPTB at <37 weeks' gestation was 30% (95% CI 27% to 34%). The risk of recurrence due to preterm premature rupture of membranes (PPROM) at <37 weeks gestation was 7% (95% CI 6% to 9%), while the risk of recurrence due to preterm labour (PTL) at <37 weeks gestation was 23% (95% CI 13% to 33%).
conclusionsThe risk of recurrent sPTB is high and is influenced by the underlying clinical pathway leading to the birth. This information is important for clinicians when discussing the recurrence risk of sPTB with their patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.