Evidence map›Paper›PMID 28679673›Full record

ArticleBMJ open2017

Risk of dementia in patients with non-haemorrhagic stroke receiving acupuncture treatment: a nationwide matched cohort study from Taiwan's National Health Insurance Research Database.

Chun-Chuan Shih, Chun-Chieh Yeh, Chaur-Jong Hu, Hsin-Long Lane, Chin-Chuan Tsai, Ta-Liang Chen, Chien-Chang Liao

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Chun-Chuan ShihSchool of Chinese Medicine for Post-Baccalaureate, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Chun-Chieh YehDepartment of Surgery, China Medical University Hospital, Taichung, Taiwan.
Chaur-Jong HuDepartment of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Hsin-Long LaneSchool of Chinese Medicine for Post-Baccalaureate, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Chin-Chuan TsaiSchool of Chinese Medicine for Post-Baccalaureate, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Ta-Liang ChenDepartment of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.
Chien-Chang LiaoDepartment of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.
I-Shou University · TWChina Medical University · TWTaipei Medical University · TWTaipei Medical University Hospital · TWTaipei Medical University-Shuang Ho Hospital · TWUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the risk of dementia in patients with stroke who did and did not receive acupuncture treatment.

designRetrospective cohort study.

settingThis study was based on Taiwan's National Health Insurance Research Database that included patients with stroke hospitalised between 1 January 2000 and 31 December 2004.

participantsWe identified 11 220 patients aged 50 years and older with newly diagnosed stroke hospitalisation. PRIMARY AND SECONDARY OUTCOME MEASURES: We compared the incident dementia during the follow-up period until the end of 2009 in patients with stroke who did and did not receive acupuncture. The adjusted HRs and 95% CIs of dementia associated with acupuncture were calculated in multivariate Cox proportional hazard regressions.

resultsAcupuncture treatment was associated with a decreased risk of dementia with multivariate adjustment (HR, 0.73; 95% CI 0.66 to 0.80), and the association was significant in both sexes and every age group, as well as in groups with ischaemic stroke, with fewer medical conditions and those hospitalised after stroke. Patients with stroke received acupuncture treatment, and conventional rehabilitation was associated with a significantly reduced risk of poststroke dementia (HR, 0.64; 95% CI 0.56 to 0.74).

conclusionsThis study raises the possibility that patients with non-haemorrhagic stroke who received acupuncture had a reduced risk of dementia. The results suggest the need for prospective sham-controlled and randomised trials to establish the efficacy of acupuncture in preventing dementia.

Indexed as

Acupuncture TherapyStroke RehabilitationAgedAged, 80 and overDatabases, FactualDementiaFemaleHospitalizationHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNational Health ProgramsRetrospective StudiesRisk AssessmentacupunctureDementiaStroke

Identifiers

PMID28679673
PMCPMC5734214
OpenAlexW2732030635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.