Evidence map›Paper›PMID 28679630›Full record

ArticleSexually transmitted infections2017

Condomless sex in HIV-diagnosed men who have sex with men in the UK: prevalence, correlates, and implications for HIV transmission.

Marina Daskalopoulou, Alison J Rodger, Andrew N Phillips, Lorraine Sherr, Jonathan Elford, Jeffrey McDonnell, Simon Edwards, Nicky Perry, Ed Wilkins, Simon Collins and 5 more

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Sexually transmitted infections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
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  16. Improving care for sexually transmitted infections.Journal of the International AIDS Society · 2019
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  20. Tobacco, Alcohol, Drug Use, and Intimate Partner Violence Among MSM Living With HIV.The Journal of the Association of Nurses in AIDS Care : JANAC
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Marina DaskalopoulouResearch Department of Infection and Population Health, University College London, London, UK.ORCID 0000-0001-9927-0358
Alison J RodgerResearch Department of Infection and Population Health, University College London, London, UK.
Andrew N PhillipsResearch Department of Infection and Population Health, University College London, London, UK.
Lorraine SherrResearch Department of Infection and Population Health, University College London, London, UK.
Jonathan ElfordCity University London, London, UK.
Jeffrey McDonnellResearch Department of Infection and Population Health, University College London, London, UK.
Simon EdwardsMortimer Market Centre, Central and North West London NHS Foundation Trust, London, UK.
Nicky PerryBrighton and Sussex University Hospitals NHS Trust, Brighton, UK.
Ed WilkinsPennine Acute Hospitals NHS Trust, Manchester, UK.
Simon CollinsHIV i-Base, London, UK.
Anne M JohnsonResearch Department of Infection and Population Health, University College London, London, UK.
William J BurmanDenver Public Health, Denver, Colorado, USA.
Andrew SpeakmanResearch Department of Infection and Population Health, University College London, London, UK.
Fiona C LampeResearch Department of Infection and Population Health, University College London, London, UK.
ASTRA Study Group
Biology of Infection · FRCentral and North West London NHS Foundation Trust · GBCity, University of London · GBDenver Public Health · USPennine Acute Hospitals NHS Trust · GBUniversity Hospitals Sussex NHS Foundation Trust · GB

Funding

Department of Health RP-PG-0608-10142Wellcome Trust
6 · The paper itself

Abstract

objectiveHIV transmission is ongoing among men who have sex with men (MSM) in the UK. Sex without a condom (condomless sex, CLS) is the main risk factor. We investigated the prevalence of and factors associated with types of CLS.

methodsCross-sectional questionnaire study in UK HIV clinics in 2011/2012 (ASTRA). MSM diagnosed with HIV for ≥3 months reported on anal and vaginal sex, CLS with HIV-serodifferent partners (CLS-D) and CLS with HIV-seroconcordant (CLS-C) partners in the previous 3 months. Mutually exclusive sexual behaviours were as follows: (1) Higher HIV risk CLS-D (not on antiretroviral therapy (ART) or clinic-recorded viral load(VL) >50 c/mL), (2) Other CLS-D, (3) CLS-C without CLS-D, (4) Condom-protected sex only and (5) No anal or vaginal sex. Associations were examined of sociodemographic, HIV-related, lifestyle, and other sexual measures with the five categories of sexual behaviour. We examined the prevalence of higher HIV risk CLS-D incorporating (in addition to ART and VL) time on ART, ART non-adherence, and recent sexually transmitted infections (STIs).

resultsAmong 2189 HIV-diagnosed MSM (87% on ART), prevalence of any CLS in the past 3 months was 38.2% (95% CI 36.2% to 40.4%) and that of any CLS-D was 16.3% (14.8%-17.9%). The five-category classification was as follows: (1) Higher HIV risk CLS-D: 4.2% (3.5% to 5.2%), (2) Other CLS-D: 12.1% (10.8% to 13.5%), (3) CLS-C without CLS-D: 21.9% (20.2% to 23.7%), (4) Condom-protected sex only: 25.4% (23.6% to 27.3%) and (5) No anal or vaginal sex: 36.4% (34.3% to 38.4%). Compared with men who reported condom-protected sex only, MSM who reported any CLS in the past 3 months had higher prevalence of STIs, chemsex-associated drug use, group sex, higher partner numbers, and lifetime hepatitis C. Prevalence of higher HIV risk CLS-D ranged from 4.2% to 7.5% according to criteria included.

conclusionCLS was prevalent among HIV-diagnosed MSM, but CLS-D with higher HIV transmission risk was overall low. CLS-D is no longer the most appropriate measure of HIV transmission risk behaviour among people with diagnosed HIV; accounting for VL is important.

Indexed as

Sexual PartnersAnti-HIV AgentsCondomsCross-Sectional StudiesDrug MonitoringHIV InfectionsHomosexuality, MaleHumansMaleMedication AdherenceMiddle AgedPrevalenceRisk-TakingRNA, ViralSexual BehaviorUnited KingdomAnti-HIV AgentsRNA, ViralDRUG MISUSEEPIDEMIOLOGY (GENERAL)GAY MENHIVSEXUAL BEHAVIOUR

Identifiers

PMID28679630
PMCPMC5739863
OpenAlexW2728718017

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.