ArticleAmerican journal of physiology. Renal physiology2017
Greater transforming growth factor-β in adult female SHR is dependent on blood pressure, but does not account for sex differences in renal T-regulatory cells.
Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Hypertension after the Menopause: What Can We Learn from Experimental Studies?Physiological research · 2023Review
- Splenocyte transfer from hypertensive donors eliminates premenopausal female protection from ANG II-induced hypertension.American journal of physiology. Renal physiology · 2022Article
- Sex differences in apoptosis do not contribute to sex differences in blood pressure or renal T cells in spontaneously hypertensive rats.Frontiers in physiology · 2022Article
- Study on the Mechanism of Bu-Shen-He-Mai Granules in Improving Renal Damage of Ageing Spontaneously Hypertensive Rats by Regulating Th17 Cell/Tregs Balance.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Sex differences in hypertension: lessons from spontaneously hypertensive rats (SHR).Clinical science (London, England : 1979) · 2021Review
- Role of activin receptor-like kinase 1 in vascular development and cerebrovascular diseases.Neural regeneration research · 2020Review
- LC-MS analysis ofRSC advances · 2020Article
- Sex-Specific Mechanisms in Inflammation and Hypertension.Current hypertension reports · 2019Review
- Understanding sex differences in long-term blood pressure regulation: insights from experimental studies and computational modeling.American journal of physiology. Heart and circulatory physiology · 2019Article
- Recent advances in sex differences in kidney function.American journal of physiology. Renal physiology · 2019Article
- Sex Differences in Renal Inflammation and Injury in High-Fat Diet-Fed Dahl Salt-Sensitive Rats.Hypertension (Dallas, Tex. : 1979) · 2018Article
- [Role of inducible costimulatory molecule-mediated Th17 cell polarization in renal fibrosis in spontaneously hypertensive rats].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
- Sex and rigor: the TGF-β blood pressure affair.American journal of physiology. Renal physiology · 2017Article
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Abstract
Female spontaneously hypertensive rats (SHR) have more renal regulatory T cells (Tregs) than males, and greater levels of Tregs in female SHR are dependent on blood pressure (BP). However, the molecular mechanism responsible for greater Tregs in female SHR is unknown. Transforming growth factor (TGF)-β is a pleiotropic cytokine critical in the differentiation of naïve T cells into Tregs, and female SHR have higher TGF-β excretion than male SHR. The goals of the current study were to test the hypotheses that
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