Evidence map›Paper›PMID 28679512›Full record

ArticleBMJ case reports2017

Guillain-Barré syndrome in association with antitumour necrosis factor therapy: a case of mistaken identity.

Kurvi Patwala, Nicholas Crump, Peter De Cruz

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Guillain-Barré syndrome.Nature reviews. Disease primers · 2024
    Article
  5. Review
  6. Article
  7. Immune-Mediated Neuropathies: Pathophysiology and Management.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kurvi PatwalaDepartment of Gastroenterology, Austin Health, Heidelberg, Australia.
Nicholas CrumpDepartment of Neurology, Austin Health, Heidelberg, Australia.
Peter De CruzDepartment of Gastroenterology, Austin Health, Heidelberg, Australia.
Austin Health · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guillain-Barré syndrome (GBS) is an immune-mediated disease characterised by evolving ascending limb weakness, sensory loss and areflexia. Two-thirds of GBS cases are associated with preceding infection. However, GBS has also been described in association with antitumour necrosis factor (TNF) therapies including infliximab and adalimumab for chronic inflammatory disorders such as rheumatoid arthritis, ankylosing spondylitis and inflammatory bowel disease. We present the case of a patient who developed GBS while undergoing treatment with adalimumab in combination with azathioprine for severe fistulising Crohn's disease, and review the literature on neurological adverse events that occur in association with anti-TNF therapy. We also propose an approach to the optimal management of patients who develop debilitating neurological sequelae in the setting of anti-TNF therapy.

Indexed as

AdalimumabAdultAnti-Inflammatory AgentsAzathioprineCrohn DiseaseGastrointestinal AgentsGuillain-Barre SyndromeHumansImmunosuppressive AgentsInfliximabMaleTumor Necrosis Factor-alphaAdalimumabAnti-Inflammatory AgentsAzathioprineGastrointestinal AgentsImmunosuppressive AgentsInfliximabTumor Necrosis Factor-alphaContraindications and precautionsDrugs: Gastrointestinal systemInflammatory bowel diseaseNeurology (drugs and medicines)Peripheral nerve disease

Identifiers

PMID28679512
PMCPMC5534643
OpenAlexW2730542138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.