Trial reportTrials2017
Practical issues regarding implementing a randomized clinical trial in a homeless population: strategies and lessons learned.
Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Varenicline Adherence and Outcomes in Homeless Smokers
Enhancing Smoking Cessation in the Homeless Population
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Homelessness and health-related outcomes: an umbrella review of observational studies and randomized controlled trials.BMC medicine · 2022Pooled it
- Interventions to reduce tobacco use in people experiencing homelessness.The Cochrane database of systematic reviews · 2020Pooled it
- The implementation of a smoking cessation and alcohol abstinence intervention for people experiencing homelessness.BMC public health · 2022Trial
- The provision of cell phones as a recruitment and retention strategy for people who inject drugs enrolling in a randomized trial.Drug and alcohol dependence · 2018Trial
- Improving post-traumatic stress symptoms in homeless-experienced women using narrative exposure therapy: a single-arm, open pilot study.European journal of psychotraumatology · 2026Article
- Observational
- Patient Perspectives on Palliative Care Outreach to Adults Living With Homelessness.JAMA network open · 2026Article
- Migrants Living in the United Kingdom and Their Perceptions of Participation in Health Research: A Mixed-Methods Study.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Prevalence of stimulant use and the role of opioid agonist treatment among people who inject drugs in France: Results from the COSINUS cohort study.Drug and alcohol review · 2025Article
- Association between psychosocial factors and co-morbid cigarette smoking and alcohol use in a population experiencing homelessness.Addictive behaviors reports · 2024Article
- Article
- Tobacco use behaviors and views on engaging in clinical trials for tobacco cessation among individuals who experience homelessness.Contemporary clinical trials communications · 2023Article
- Reducing lifestyle risk behaviours in disadvantaged groups in high-income countries: A scoping review of systematic reviews.Preventive medicine · 2022Article
- Evaluating a specialist primary care service for patients experiencing homelessness: a qualitative study.BJGP open · 2020Article
- Challenges and Opportunities to Meet the Mental Health Needs of Underserved and Disenfranchised Populations in the United States.Focus (American Psychiatric Publishing) · 2020Article
- "It's a hard thing to manage when you're homeless": the impact of the social environment on smoking cessation for smokers experiencing homelessness.BMC public health · 2019Article
- Lessons learned from conducting a community-based, nurse-led HIV prevention trial with youth experiencing homelessness: Pivots and pitfalls.Public health nursing (Boston, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
There is a critical need for objective data to guide effective health promotion and care for homeless populations. However, many investigators exclude homeless populations from clinical trials due to practical concerns about conducting research with this population. This report is based on our experience and lessons learned while conducting two large NIH-funded randomized controlled trials targeting smoking cessation among persons who are homeless. The current report also addresses challenges when conducting clinical trials among homeless populations and offers potential solutions. Homeless individuals face several challenges including the need to negotiate daily access to food, clothing, and shelter. Some of the critical issues investigators encounter include recruitment and retention obstacles; cognitive impairment, mental health and substance abuse disorders; transportation and scheduling challenges; issues pertaining to adequate study compensation; the need for safety protocols for study staff; and issues related to protecting the wellbeing of these potentially vulnerable adults. Anticipating realistic conditions in which to conduct studies with participants who are homeless will help investigators to design efficient protocols and may improve the feasibility of conducting clinical trials involving homeless populations and the quality of the data collected by the researchers.
trial registrationClinicalTrials.gov, ID: NCT00786149 . Registered on 5 November 2008; ClinicalTrials.gov, ID: NCT01932996 . Registered on 20 November 2014.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.