ArticleThe Journal of international medical research2018
Altered brain network centrality in patients with adult comitant exotropia strabismus: A resting-state fMRI study.
Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 50 citations in OpenAlex.
- Altered Spontaneous Brain Activity in Adolescents and Adults with Comitant Strabismus and Strabismic Amblyopia.Ophthalmology science · 2026Article
- Abnormal white matter in the visual pathways of strabismus with and without amblyopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Aberrant brain functional connectivity in patients with dysthyroid optic neuropathy: a resting-state fMRI study.Frontiers in neuroscience · 2026Article
- Central alterations of brain networks in patients with optic neuritis: a resting state fMRI study.International journal of ophthalmology · 2025Article
- Visual and auditory attention defects in children with intermittent exotropia.Italian journal of pediatrics · 2024Article
- Alternations of interhemispheric functional connectivity in patients with acute acquired concomitant esotropia: a resting state fMRI study using voxel-mirrored homotopic connectivity.Frontiers in neuroscience · 2024Article
- Spontaneous changes in brain network centrality in patients with pathological myopia: A voxel-wise degree centrality analysis.CNS neuroscience & therapeutics · 2023Article
- Altered interhemispheric functional connectivity in patients with comitant exotropia before and after surgery: a resting-state fMRI study.Frontiers in human neuroscience · 2023Article
- Machine learning analysis reveals aberrant dynamic changes in amplitude of low-frequency fluctuations among patients with retinal detachment.Frontiers in neuroscience · 2023Article
- Article
- Gray matter volume alterations in patients with strabismus and amblyopia: voxel-based morphometry study.Scientific reports · 2022Article
- Alteration of Degree Centrality in Adolescents With Early Blindness.Frontiers in human neuroscience · 2022Article
- Altered Brain Activity in Patients With Comitant Strabismus Detected by Analysis of the Fractional Amplitude of Low-Frequency Fluctuation: A Resting-State Functional MRI Study.Frontiers in human neuroscience · 2022Article
- Study of Geometric Illusory Visual Perception - A New Perspective in the Functional Evaluation of Children With Strabismus.Frontiers in human neuroscience · 2022Article
- Altered Homotopic Connectivity in the Cerebellum Predicts Stereopsis Dysfunction in Patients With Comitant Exotropia.Frontiers in human neuroscience · 2022Article
- Neuroimaging Markers of Chronic Eye Diseases and Their Application Values.Frontiers in neurology · 2022Review
- Abnormal developmental trends of functional connectivity in young children with infantile esotropia.Frontiers in neuroscience · 2022Article
- Children with strabismus and amblyopia presented abnormal spontaneous brain activities measured through fractional amplitude of low-frequency fluctuation (fALFF).Frontiers in neurology · 2022Article
- Brain Functional Connectivity Changes in Patients with Acute Eye Pain: A Resting-State Functional Magnetic Resonance Imaging (fMRI) Study.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Alternations of interhemispheric functional connectivity in children with strabismus and amblyopia: a resting-state fMRI study.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective To investigate the underlying functional network brain-activity changes in patients with adult comitant exotropia strabismus (CES) and the relationship with clinical features using the voxel-wise degree centrality (DC) method. Methods A total of 30 patients with CES (17 men, 13 women), and 30 healthy controls (HCs; 17 men, 13 women) matched in age, sex, and education level participated in the study. DC was used to evaluate spontaneous brain activity. Receiver operating characteristic (ROC) curve analysis was conducted to distinguish CESs from HCs. The relationship between mean DC values in various brain regions and behavioral performance was examined with correlation analysis. Results Compared with HCs, CES patients exhibited decreased DC values in the right cerebellum posterior lobe, right inferior frontal gyrus, right middle frontal gyrus and right superior parietal lobule/primary somatosensory cortex (S1), and increased DC values in the right superior temporal gyrus, bilateral anterior cingulate, right superior temporal gyrus, and left inferior parietal lobule. However, there was no correlation between mean DC values and behavioral performance in any brain regions. Conclusions Adult comitant exotropia strabismus is associated with abnormal brain network activity in various brain regions, possibly reflecting the pathological mechanisms of ocular motility disorders in CES.
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