ReviewPerspectives on psychological science : a journal of the Association for Psychological Science2017
Inflammation, Self-Regulation, and Health: An Immunologic Model of Self-Regulatory Failure.
Review in Perspectives on psychological science : a journal of the Association for Psychological Science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Oxytocin, cortisol, and cognitive control during acute and naturalistic stress.Stress (Amsterdam, Netherlands) · 2021Trial
- Only vulnerable adults show change in chronic low-grade inflammation after contemplative mental training: evidence from a randomized clinical trial.Scientific reports · 2019Trial
- Countering the forgetting of novel health information with 'social boosting'.SSM - population health · 2026Article
- Investigating the Moderating Effect of Attitudes Toward One's Own Aging on the Association Between Body Mass Index and Executive Function in Older Adults.Geriatrics (Basel, Switzerland) · 2025Article
- Cortisol, Anxiety, and TNFα Mediate the Relationship Between BMI and Executive Functions.Stress and health : journal of the International Society for the Investigation of Stress · 2025Article
- Lifetime stressor exposure is related to suicidality in autistic adults: A multinational study.Autism : the international journal of research and practice · 2025Article
- Article
- Affective-cognitive circuits in postoperative appetite reduction: an adaptive neuroimmune response to surgical stress.Frontiers in neuroscience · 2025Review
- Lifetime adversity predicts depression, anxiety, and cognitive impairment in a nationally representative sample of older adults in the United States.Journal of clinical psychology · 2024Article
- Body mass index-dependent shifts along large-scale gradients in human cortical organization explain dietary regulatory success.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Heightened neural activity and functional connectivity responses to social rejection in female adolescents at risk for depression: Testing the Social Signal Transduction Theory of Depression.Journal of affective disorders · 2024Article
- Addressing the links between and internal vs. external regulation factors, achievement emotions and gender in problematic use of ICT at university.Frontiers in psychology · 2024Article
- Relating neighborhood deprivation to childhood obesity in the ABCD study: Evidence for theories of neuroinflammation and neuronal stress.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023Article
- Understanding the combined effects of sleep deprivation and acute social stress on cognitive performance using a comprehensive approach.Brain, behavior, & immunity - health · 2023Article
- Variation in executive function relates to BMI increases in youth who were initially of a healthy weight in the ABCD Study.Obesity (Silver Spring, Md.) · 2023Article
- Social Safety Theory: Conceptual foundation, underlying mechanisms, and future directions.Health psychology review · 2023Article
- Why is subjective stress severity a stronger predictor of health than stressor exposure? A preregistered two-study test of two hypotheses.Stress and health : journal of the International Society for the Investigation of Stress · 2023Article
- The Association of Obesity and Overweight with Executive Functions in Community-Dwelling Older Women.International journal of environmental research and public health · 2023Article
- Adherence to Screen Time and Physical Activity Guidelines is Associated with Executive Function in US Toddlers Participating in the STRONG Kids 2 Birth Cohort Study.The Journal of pediatrics · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Self-regulation is a fundamental human process that refers to multiple complex methods by which individuals pursue goals in the face of distractions. Whereas superior self-regulation predicts better academic achievement, relationship quality, financial and career success, and lifespan health, poor self-regulation increases a person's risk for negative outcomes in each of these domains and can ultimately presage early mortality. Given its centrality to understanding the human condition, a large body of research has examined cognitive, emotional, and behavioral aspects of self-regulation. In contrast, relatively little attention has been paid to specific biologic processes that may underlie self-regulation. We address this latter issue in the present review by examining the growing body of research showing that components of the immune system involved in inflammation can alter neural, cognitive, and motivational processes that lead to impaired self-regulation and poor health. Based on these findings, we propose an integrated, multilevel model that describes how inflammation may cause widespread biobehavioral alterations that promote self-regulatory failure. This immunologic model of self-regulatory failure has implications for understanding how biological and behavioral factors interact to influence self-regulation. The model also suggests new ways of reducing disease risk and enhancing human potential by targeting inflammatory processes that affect self-regulation.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.