Trial reportJournal of applied oral science : revista FOB
In situ effect of CPP-ACP chewing gum upon erosive enamel loss.
Trial report in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Quantitative and spectroscopic assessment of early-stage enamel erosion induced by popular acidic beverages.BMC oral health · 2025Article
- Evaluation of enamel remineralization potential and anticariogenic efficacy of polydopamine coated biogenic amorphous calcium phosphate.Clinical oral investigations · 2025Article
- Research progress of biomimetic materials in oral medicine.Journal of biological engineering · 2023Review
- Development of Root Caries Prevention by Nano-Hydroxyapatite Coating and Improvement of Dentin Acid Resistance.Materials (Basel, Switzerland) · 2022Article
- Improved Enamel Acid Resistance Using Biocompatible Nano-Hydroxyapatite Coating Method.Materials (Basel, Switzerland) · 2022Article
- Film-Forming Polymers for Tooth Erosion Prevention.Polymers · 2022Review
- Effect of Two Methods of Remineralization and Resin Infiltration on Surface Hardness of Artificially Induced Enamel Lesions.Journal of dentistry (Shiraz, Iran) · 2020Article
- The use of a new calcium mesoporous silica nanoparticle versus calcium and/or fluoride products in reducing the progression of dental erosion.Journal of applied oral science : revista FOB · 2020Article
- Prevention of erosive tooth wear: targeting nutritional and patient-related risks factors.British dental journal · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis in situ study investigated the ability of a CPP-ACP chewing gum in preventing erosive enamel loss. Material and Methods: During three experimental crossover phases (one phase per group) of seven days each, eight volunteers wore palatal devices with human enamel blocks. The groups were: GI - Sugar free chewing gum with CPP-ACP; GII - Conventional sugar free chewing gum; and GIII - No chewing gum (control). Erosive challenge was extraorally performed by immersion of the enamel blocks in cola drink (5 min, 4x/day). After each challenge, in groups CPP and No CPP, volunteers chewed one unit of the corresponding chewing gum for 30 minutes. Quantitative analysis of enamel loss was performed by profilometry (µm). Data were analyzed by Repeated-Measures ANOVA and Tukey's test (p<0.05).
resultsThe use of chewing gum (CPP and No CPP) resulted in lower erosive enamel loss compared with the control group (p<0.05). CPP-ACP chewing gum (CPP) did not improve the protection against erosive enamel loss compared with conventional chewing gum (No CPP) (p>0.05).
conclusionThe CPP-ACP chewing gum was not able to enhance the anti-erosive effect of conventional chewing gum against enamel loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.