Evidence map›Paper›PMID 28678874›Full record

ArticlePloS one2017

Molecular characteristics of mcr-1-carrying plasmids and new mcr-1 variant recovered from polyclonal clinical Escherichia coli from Argentina and Canada.

Nathalie Tijet, Diego Faccone, Melina Rapoport, Christine Seah, Fernando Pasterán, Paola Ceriana, Ezequiel Albornoz, Alejandra Corso, Alejandro Petroni, Roberto G Melano

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Global High-RiskInternational journal of microbiology · 2026
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  6. Sporadic cloneFrontiers in cellular and infection microbiology · 2024
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  7. UropathogenicMicroorganisms · 2023
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  8. More thanFrontiers in cellular and infection microbiology · 2023
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  9. Characterization of DiarreaghenicAntibiotics (Basel, Switzerland) · 2022
    Article
  10. Global epidemiology, genetic environment, risk factors and therapeutic prospects ofFrontiers in cellular and infection microbiology · 2022
    Review
  11. Genome Sequencing Identifies Previously Unrecognized Klebsiella pneumoniae Outbreaks in Neonatal Intensive Care Units in the Philippines.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  12. Article
  13. Genomic diversity ofMicrobial genomics · 2021
    Article
  14. Article
  15. Emergence of Multidrug-ResistantFrontiers in cellular and infection microbiology · 2021
    Article
  16. Review
  17. Occurrence and Molecular Characteristics ofAnimals : an open access journal from MDPI · 2020
    Article
  18. Article
  19. Plasmidic resistance to colistin mediated byRevista panamericana de salud publica = Pan American journal of public health · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nathalie TijetPublic Health Ontario Laboratory, Toronto, Ontario, Canada.
Diego FacconeServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Melina RapoportServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Christine SeahPublic Health Ontario Laboratory, Toronto, Ontario, Canada.
Fernando PasteránServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Paola CerianaServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Ezequiel AlbornozServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Alejandra CorsoServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Alejandro PetroniServicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran", Buenos Aires, Argentina.
Roberto G MelanoPublic Health Ontario Laboratory, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-0268-1028

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have characterized nine mcr-1-harboring plasmids from clinical Escherichia coli isolates previously described in Argentina and Canada. Three of these plasmids carried a mcr-1-variant called here mcr-1.5. All these E. coli isolates were not clonally related and were recovered in different years and locations. However, their mcr-1-harboring plasmids showed high identity among them and to others characterized in other countries, which strongly suggests that this plasmid-type is playing an important role in spreading this mechanism of resistance to polymyxins.

Indexed as

Amino Acid SequenceAnti-Bacterial AgentsArgentinaCanadaDNA, BacterialDrug Resistance, BacterialEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsEthanolaminephosphotransferaseGenetic VariationGenotypeHumansMicrobial Sensitivity TestsPlasmidsPolymerase Chain ReactionAnti-Bacterial AgentsDNA, BacterialEscherichia coli ProteinsEthanolaminephosphotransferaseMCR-1 protein, E coliPolymyxins

Identifiers

PMID28678874
PMCPMC5498056

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.