ArticlePloS one2017
Malaria in Dielmo, a Senegal village: Is its elimination possible after seven years of implementation of long-lasting insecticide-treated nets?
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- [West African tick-borne relapsing fever, a neglected disease of major public health importance in Senegal].Medecine tropicale et sante internationale · 2025Pooled it
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- Spatio-temporal dynamics of malaria incidence in children under five years of age and correlation with meteorological variability in the North and Far North regions of Cameroon between 2015-2022.Parasite epidemiology and control · 2025Article
- Genetic diversity and natural selection of Plasmodium falciparum Pf41 vaccine candidate in clinical isolates from Senegal.Scientific reports · 2025Article
- Insecticide Resistance and Target-Site MutationsGenes · 2024Article
- Malaria epidemics associated with low net use in preadolescent and young adult population in Dielmo (Senegal), a malaria pre-elimination area.Parasites & vectors · 2024Article
- Host feeding preferences of malaria vectors in an area of low malaria transmission.Scientific reports · 2023Article
- Rebound of multiple infections and prevalence of anti-malarial resistance associated markers following malaria upsurges in Dielmo village, Senegal, West Africa.Malaria journal · 2023Article
- How many mosquito nets are needed to maintain universal coverage: an update.Malaria journal · 2023Article
- Quantitative Polymerase Chain Reaction from Malaria Rapid Diagnostic Tests to Detect Borrelia crocidurae, the Agent of Tick-Borne Relapsing Fever, in Febrile Patients in Senegal.The American journal of tropical medicine and hygiene · 2023Article
- Article
- Incidence of Plasmodium falciparum malaria infection in 6-month to 45-year-olds on selected areas of Bioko Island, Equatorial Guinea.Malaria journal · 2021Article
- Tick-borne relapsing fever Borreliosis, a major public health problem overlooked in Senegal.PLoS neglected tropical diseases · 2021Article
- A survey of knowledge, attitudes and practices regarding malaria and bed nets on Bubaque Island, Guinea-Bissau.Malaria journal · 2020Article
- Anopheles arabiensis and Anopheles funestus biting patterns in Dielmo, an area of low level exposure to malaria vectors.Malaria journal · 2020Article
- Spatio-temporal variation of malaria hotspots in Central Senegal, 2008-2012.BMC infectious diseases · 2020Article
- Application of Functional Data Analysis to Identify Patterns of Malaria Incidence, to Guide Targeted Control Strategies.International journal of environmental research and public health · 2020Article
- Geo-Epidemiology of Malaria at the Health Area Level, Dire Health District, Mali, 2013-2017.International journal of environmental research and public health · 2020Article
- Practical example of multiple antibody screening for evaluation of malaria control strategies.Malaria journal · 2020Article
Corrections and comments
- Expression of concern · 2022-12-13Investigation by Journal/Publisher ·
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe malaria burden has decreased significantly in recent years in Africa through the widespread use of artemisinin-based combination therapy (ACT) and long-lasting insecticide-treated nets (LLINs). However, the occurrence of malaria resurgences, the loss of immunity of exposed populations constitute among other factors, serious concerns about the future of malaria elimination efforts. This study investigated the evolution of malaria morbidity in Dielmo (Senegal) before and after the implementation of LLINs.
methodsA longitudinal study was carried out in Dielmo over eight years, from July 2007 to July 2015. In July 2008, LLINs were offered to all villagers, and in July 2011 and August 2014 the LLINs were renewed. A survey on LLINs use was done each quarter of the year. Thick smears stained with Giemsa, a rapid diagnostic test (RDT) and quantitative polymerase chain reaction (PCR) methods were performed for all cases of fever to assess malaria clinical attacks. Malaria cases were treated with ACT since June 2006.
resultsMalaria morbidity has decreased significantly since the implementation of LLINs in Dielmo, together with ACT. However, malaria resurgences have occurred twice during the seven years of LLINs use. These resurgences occurred the first time during the third year after the introduction of LLINs (aIRR (adjusted incidence-rate ratio) [95%CI] = 5.90 [3.53; 9.88] p< 0.001) and a second time during the third year after the renewal of LLINs (aIRR [95%CI] = 5.60 [3.34; 9.39] p< 0.001). Sixty-nine percent (69%) of the nets tested for their long-lasting insecticidal activity remained effective after 3 years of use.
conclusionGood management of malaria cases by the use of ACT as first-line treatment against malaria in addition to the use of LLINs has significantly reduced malaria in Dielmo and allowed to reach the phase of pre-elimination of the disease. However, the occurrence of malaria resurgences raised serious concerns about malaria elimination, which would require additional tools in this village.
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