Evidence map›Paper›PMID 28678777›Full record

ArticleNature2017

Neurodegeneration: Taming tangled tau.

David S Eisenberg, Michael R Sawaya

Abstract readNewsComment
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. International journal of molecular sciences · 2024
    Article
  6. Article
  7. Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Review
  9. A direct interaction between RhoGDIα/Tau alleviates hyperphosphorylation of Tau in Alzheimer's disease and vascular dementia.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Physical Biology of Axonal Damage.Frontiers in cellular neuroscience · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

David S EisenbergHoward Hughes Medical Institute and the UCLA-DOE Institute, and in the Departments of Biological Chemistry and Chemistry &Biochemistry, University of California Los Angeles, Los Angeles 90095-1570, USA.
Michael R SawayaHoward Hughes Medical Institute and the UCLA-DOE Institute, and in the Departments of Biological Chemistry and Chemistry &Biochemistry, University of California Los Angeles, Los Angeles 90095-1570, USA.

Funding

Structural Biology of Amyloid DiseaseR01AG029430 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EISENBERG, DAVID · 2007 to 2016
$3.9M
Howard Hughes Medical InstituteNIA NIH HHS R01 AG029430
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer Diseasetau ProteinsHumansNerve Degenerationtau Proteins

Identifiers

PMID28678777
PMCPMC6400062

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.